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Age-differentiated incentives for adaptive behavior during epidemics produce oscillatory and chaotic dynamics

Heterogeneity in contact patterns, mortality rates, and transmissibility among and between different age classes can have significant effects on epidemic outcomes. Adaptive behavior in response to the spread of an infectious pathogen may give rise to complex epidemiological dynamics. Here we model a...

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Autores principales: Arthur, Ronan F., Levin, May, Labrogere, Alexandre, Feldman, Marcus W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503720/
https://www.ncbi.nlm.nih.gov/pubmed/37669282
http://dx.doi.org/10.1371/journal.pcbi.1011217
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author Arthur, Ronan F.
Levin, May
Labrogere, Alexandre
Feldman, Marcus W.
author_facet Arthur, Ronan F.
Levin, May
Labrogere, Alexandre
Feldman, Marcus W.
author_sort Arthur, Ronan F.
collection PubMed
description Heterogeneity in contact patterns, mortality rates, and transmissibility among and between different age classes can have significant effects on epidemic outcomes. Adaptive behavior in response to the spread of an infectious pathogen may give rise to complex epidemiological dynamics. Here we model an infectious disease in which adaptive behavior incentives, and mortality rates, can vary between two and three age classes. The model indicates that age-dependent variability in infection aversion can produce more complex epidemic dynamics at lower levels of pathogen transmissibility and that those at less risk of infection can still drive complexity in the dynamics of those at higher risk of infection. Policymakers should consider the interdependence of such heterogeneous groups when making decisions.
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spelling pubmed-105037202023-09-16 Age-differentiated incentives for adaptive behavior during epidemics produce oscillatory and chaotic dynamics Arthur, Ronan F. Levin, May Labrogere, Alexandre Feldman, Marcus W. PLoS Comput Biol Research Article Heterogeneity in contact patterns, mortality rates, and transmissibility among and between different age classes can have significant effects on epidemic outcomes. Adaptive behavior in response to the spread of an infectious pathogen may give rise to complex epidemiological dynamics. Here we model an infectious disease in which adaptive behavior incentives, and mortality rates, can vary between two and three age classes. The model indicates that age-dependent variability in infection aversion can produce more complex epidemic dynamics at lower levels of pathogen transmissibility and that those at less risk of infection can still drive complexity in the dynamics of those at higher risk of infection. Policymakers should consider the interdependence of such heterogeneous groups when making decisions. Public Library of Science 2023-09-05 /pmc/articles/PMC10503720/ /pubmed/37669282 http://dx.doi.org/10.1371/journal.pcbi.1011217 Text en © 2023 Arthur et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Arthur, Ronan F.
Levin, May
Labrogere, Alexandre
Feldman, Marcus W.
Age-differentiated incentives for adaptive behavior during epidemics produce oscillatory and chaotic dynamics
title Age-differentiated incentives for adaptive behavior during epidemics produce oscillatory and chaotic dynamics
title_full Age-differentiated incentives for adaptive behavior during epidemics produce oscillatory and chaotic dynamics
title_fullStr Age-differentiated incentives for adaptive behavior during epidemics produce oscillatory and chaotic dynamics
title_full_unstemmed Age-differentiated incentives for adaptive behavior during epidemics produce oscillatory and chaotic dynamics
title_short Age-differentiated incentives for adaptive behavior during epidemics produce oscillatory and chaotic dynamics
title_sort age-differentiated incentives for adaptive behavior during epidemics produce oscillatory and chaotic dynamics
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503720/
https://www.ncbi.nlm.nih.gov/pubmed/37669282
http://dx.doi.org/10.1371/journal.pcbi.1011217
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