Perioperative Myocardial Infarction Following Dabigatran Reversal With Idarucizumab in a Patient Undergoing Orthotopic Liver Transplantation

Insufficient information is available regarding the administration of anticoagulants, specifically direct oral anticoagulants, in individuals with cirrhosis awaiting liver transplantation. In this report, we present a case of a 66-year-old male with atrial fibrillation treated with dabigatran who re...

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Autores principales: Barroso, Alex, Martinez-Gonzalez, M. Carmen, Knowlson, Nathanael, Miguel, Alba M., Perez, Gonzalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Anesthesiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503784/
https://www.ncbi.nlm.nih.gov/pubmed/37719481
http://dx.doi.org/10.7759/cureus.43531
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author Barroso, Alex
Martinez-Gonzalez, M. Carmen
Knowlson, Nathanael
Miguel, Alba M.
Perez, Gonzalo
author_facet Barroso, Alex
Martinez-Gonzalez, M. Carmen
Knowlson, Nathanael
Miguel, Alba M.
Perez, Gonzalo
author_sort Barroso, Alex
collection PubMed
description Insufficient information is available regarding the administration of anticoagulants, specifically direct oral anticoagulants, in individuals with cirrhosis awaiting liver transplantation. In this report, we present a case of a 66-year-old male with atrial fibrillation treated with dabigatran who received idarucizumab prior to orthotopic liver transplantation. Hemostatic status was monitored throughout the procedure with both conventional hemostatic tests and point-of-care viscoelastic hemostatic assays. The patient suffered an intraoperative myocardial infarction, which could be related to the use of idarucizumab.
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spelling pubmed-105037842023-09-16 Perioperative Myocardial Infarction Following Dabigatran Reversal With Idarucizumab in a Patient Undergoing Orthotopic Liver Transplantation Barroso, Alex Martinez-Gonzalez, M. Carmen Knowlson, Nathanael Miguel, Alba M. Perez, Gonzalo Cureus Anesthesiology Insufficient information is available regarding the administration of anticoagulants, specifically direct oral anticoagulants, in individuals with cirrhosis awaiting liver transplantation. In this report, we present a case of a 66-year-old male with atrial fibrillation treated with dabigatran who received idarucizumab prior to orthotopic liver transplantation. Hemostatic status was monitored throughout the procedure with both conventional hemostatic tests and point-of-care viscoelastic hemostatic assays. The patient suffered an intraoperative myocardial infarction, which could be related to the use of idarucizumab. Cureus 2023-08-15 /pmc/articles/PMC10503784/ /pubmed/37719481 http://dx.doi.org/10.7759/cureus.43531 Text en Copyright © 2023, Barroso et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Anesthesiology
Barroso, Alex
Martinez-Gonzalez, M. Carmen
Knowlson, Nathanael
Miguel, Alba M.
Perez, Gonzalo
Perioperative Myocardial Infarction Following Dabigatran Reversal With Idarucizumab in a Patient Undergoing Orthotopic Liver Transplantation
title Perioperative Myocardial Infarction Following Dabigatran Reversal With Idarucizumab in a Patient Undergoing Orthotopic Liver Transplantation
title_full Perioperative Myocardial Infarction Following Dabigatran Reversal With Idarucizumab in a Patient Undergoing Orthotopic Liver Transplantation
title_fullStr Perioperative Myocardial Infarction Following Dabigatran Reversal With Idarucizumab in a Patient Undergoing Orthotopic Liver Transplantation
title_full_unstemmed Perioperative Myocardial Infarction Following Dabigatran Reversal With Idarucizumab in a Patient Undergoing Orthotopic Liver Transplantation
title_short Perioperative Myocardial Infarction Following Dabigatran Reversal With Idarucizumab in a Patient Undergoing Orthotopic Liver Transplantation
title_sort perioperative myocardial infarction following dabigatran reversal with idarucizumab in a patient undergoing orthotopic liver transplantation
topic Anesthesiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503784/
https://www.ncbi.nlm.nih.gov/pubmed/37719481
http://dx.doi.org/10.7759/cureus.43531
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