Cargando…

Disentangling accelerated cognitive decline from the normal aging process and unraveling its genetic components: A neuroimaging-based deep learning approach

BACKGROUND: The progressive cognitive decline that is an integral component of AD unfolds in tandem with the natural aging process. Neuroimaging features have demonstrated the capacity to distinguish cognitive decline changes stemming from typical brain aging and Alzheimer’s disease between differen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dai, Yulin, Yu-Chun, Hsu, Fernandes, Brisa S., Zhang, Kai, Xiaoyang, Li, Enduru, Nitesh, Liu, Andi, Manuel, Astrid M, Jiang, Xiaoqian, Zhao, Zhongming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Journal Experts 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503860/ https://www.ncbi.nlm.nih.gov/pubmed/37720047 http://dx.doi.org/10.21203/rs.3.rs-3328861/v1

Ejemplares similares

Genetic overlap between Alzheimer’s disease and immune-mediated diseases: An atlas of shared genetic determinants and biological convergence
por: Fernandes, Brisa, et al.
Publicado: (2023)

The kynurenine pathway in Alzheimer’s disease: a meta-analysis of central and peripheral levels
por: Fernandes, Brisa S., et al.
Publicado: (2023)

Unraveling the intercellular communication disruption and key pathways in Alzheimer’s disease: An integrative study of single-nucleus transcriptomes and genetic association
por: Liu, Andi, et al.
Publicado: (2023)

Genetically-regulated pathway-polygenic risk score (GRPa-PRS): A risk stratification method to identify genetically regulated pathways in polygenic diseases
por: Li, Xiaoyang, et al.
Publicado: (2023)

Persistent accelerations disentangle Lagrangian turbulence
por: Bentkamp, Lukas, et al.
Publicado: (2019)

Prioritization of risk genes in multiple sclerosis by a refined Bayesian framework followed by tissue-specificity and cell type feature assessment
por: Liu, Andi, et al.
Publicado: (2022)

Disentangling the spatial and temporal causes of decline in a bird population
por: Plard, Floriane, et al.
Publicado: (2020)

Multimodal Neuroimaging Predictors of Gait Decline
por: Sargent, Lana, et al.
Publicado: (2020)

Fostering precision psychiatry through bioinformatics
por: Fernandes, Brisa S., et al.
Publicado: (2021)

Disentangling input and output-related components of spatial neglect
por: Loetscher, Tobias, et al.
Publicado: (2012)

Disentangling the Phylogenetic and Ecological Components of Spider Phenotypic Variation
por: Gonçalves-Souza, Thiago, et al.
Publicado: (2014)

WebCSEA: web-based cell-type-specific enrichment analysis of genes
por: Dai, Yulin, et al.
Publicado: (2022)

Advancements in Neuroimaging to Unravel Biological and Molecular Features of Brain Tumors
por: Sanvito, Francesco, et al.
Publicado: (2021)

Neuroimaging in normal pressure hydrocephalus
por: Damasceno, Benito Pereira
Publicado: (2015)

Correction: Disentangling the Phylogenetic and Ecological Components of Spider Phenotypic Variation
Publicado: (2014)

Structural Neuroimaging Markers of Cognitive Decline in Parkinson's Disease
por: Hanganu, Alexandru, et al.
Publicado: (2016)

Normalized lifespan inequality: disentangling the longevity–lifespan variability nexus
por: Permanyer, Iñaki, et al.
Publicado: (2022)

Advanced network neuroimaging as an approach to unravel the pathophysiology of restless legs syndrome
por: Kassubek, Jan
Publicado: (2022)

CSEA-DB: an omnibus for human complex trait and cell type associations
por: Dai, Yulin, et al.
Publicado: (2020)

Manual Dexterity and Aging: A Pilot Study Disentangling Sensorimotor From Cognitive Decline
por: Carment, Loic, et al.
Publicado: (2018)

Disentangling the Effects of Spinal Cord Injury and Related Neuropathic Pain on Supraspinal Neuroplasticity: A Systematic Review on Neuroimaging
por: Huynh, Vincent, et al.
Publicado: (2020)

Importance of neuroimaging in normal tension glaucoma
por: Sharma, Jaideep, et al.
Publicado: (2020)

Progression in Neuroimaging of Normal Pressure Hydrocephalus
por: Yin, Rui, et al.
Publicado: (2021)

Nonlinear independent component analysis for principled disentanglement in unsupervised deep learning
por: Hyvärinen, Aapo, et al.
Publicado: (2023)

Cognitive and Neuroimaging Profiles of Individuals With Dual Decline in Memory and Gait
por: Tian, Qu, et al.
Publicado: (2020)

The neuroimaging of neurodegenerative and vascular disease in the secondary prevention of cognitive decline
por: Schaeffer, Morgan J., et al.
Publicado: (2021)

Perspective: Stepping Stones to Unraveling the Pathophysiology of Mal de Debarquement Syndrome with Neuroimaging
por: Mucci, Viviana, et al.
Publicado: (2018)

Unravelling insect declines: can space replace time?
por: Blüthgen, Nico, et al.
Publicado: (2022)

Neuroimaging of Meckel’s cave in normal and disease conditions
por: Malhotra, Ajay, et al.
Publicado: (2018)

Neuroimaging advances regarding subjective cognitive decline in preclinical Alzheimer’s disease
por: Wang, Xiaoqi, et al.
Publicado: (2020)

Study protocol: a comprehensive multi-method neuroimaging approach to disentangle developmental effects and individual differences in second language learning
por: Menks, W. M., et al.
Publicado: (2022)

Distributional independent component analysis for diverse neuroimaging modalities
por: Wu, Ben, et al.
Publicado: (2021)

Disentangling non-specific and specific transgenerational immune priming components in host–parasite interactions
por: Ben-Ami, Frida, et al.
Publicado: (2020)

Adaptive laboratory evolution and independent component analysis disentangle complex vancomycin adaptation trajectories
por: Fait, Anaëlle, et al.
Publicado: (2022)

Drug-Target Network Study Reveals the Core Target-Protein Interactions of Various COVID-19 Treatments
por: Dai, Yulin, et al.
Publicado: (2022)

Unravelling the relationship between amyloid accumulation and brain network function in normal aging and very mild cognitive decline: a longitudinal analysis
por: Moffat, Gemma, et al.
Publicado: (2022)

Unraveling Diagnostic Biomarkers of Schizophrenia Through Structure-Revealing Fusion of Multi-Modal Neuroimaging Data
por: Acar, Evrim, et al.
Publicado: (2019)

Microstructural Neuroimaging of Frailty in Cognitively Normal Older Adults
por: Tian, Qu, et al.
Publicado: (2020)

Results of Neuroimaging in Patients with Atypical Normal-Tension Glaucoma
por: Kosior-Jarecka, Ewa, et al.
Publicado: (2020)

Microstructural Neuroimaging of Frailty in Cognitively Normal Older Adults
por: Tian, Qu, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_kn73t8rn97s3679gls280t60e7