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Synthesis, predictions of drug-likeness, and pharmacokinetic properties of some chiral thioureas as potent enzyme inhibition agents
A series of chiral thioureas (1 – 17) were synthesized from and tested for their anticholinesterase, tyrosinase, and urease enzyme inhibitor activities. Various phenylisothiocyanates were added to solution of l-cysteine in methanol: water (1 : 1 v/v) at room temperature and stirred for 24 h. The pre...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Scientific and Technological Research Council of Turkey (TUBITAK)
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503972/ https://www.ncbi.nlm.nih.gov/pubmed/37720601 http://dx.doi.org/10.55730/1300-0527.3358 |