Cargando…

A systematic review of RdRp of SARS-CoV-2 through artificial intelligence and machine learning utilizing structure-based drug design strategy

Since the coronavirus disease has been declared a global pandemic, it had posed a challenge among researchers and raised common awareness and collaborative efforts towards finding the solution. Caused by severe acute respiratory coronavirus syndrome-2 (SARS-CoV-2), coronavirus drug design strategy n...

Descripción completa

Detalles Bibliográficos
Autores principales:	IMTIAZ, Fariha, PASHA, Mustafa Kamal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Scientific and Technological Research Council of Turkey (TUBITAK) 2021
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10503974/ https://www.ncbi.nlm.nih.gov/pubmed/37720604 http://dx.doi.org/10.55730/1300-0527.3355

Ejemplares similares

RdRp or RT, That is the Question
por: Peyambari, Mahtab, et al.
Publicado: (2021)

Aging correlates with lower threshold cycle values for RdRP/RdRP+S genes during molecular detection of SARS-CoV-2
por: Mikuła-Pietrasik, Justyna, et al.
Publicado: (2021)

SARS-CoV-2 RdRp Inhibitors Selected from a Cell-Based SARS-CoV-2 RdRp Activity Assay System
por: Min, Jung Sun, et al.
Publicado: (2021)

RdRp mutations are associated with SARS-CoV-2 genome evolution
por: Eskier, Doğa, et al.
Publicado: (2020)

The potential of Paritaprevir and Emetine as inhibitors of SARS-CoV-2 RdRp
por: Gurung, Arun Bahadur, et al.
Publicado: (2021)

A hypothesis on designing strategy of effective RdRp inhibitors for the treatment of SARS-CoV-2
por: Chaube, Udit, et al.
Publicado: (2022)

Snapshots of a Non-Canonical RdRP in Action
por: Ferrero, Diego S., et al.
Publicado: (2021)

In silico investigation to identify potential small molecule inhibitors of the RNA-dependent RNA polymerase (RdRp) nidovirus RdRp-associated nucleotidyltransferase domain
por: Pitsillou, Eleni, et al.
Publicado: (2021)

Mechanistic insight on the remdesivir binding to RNA-Dependent RNA polymerase (RdRp) of SARS-cov-2
por: Arba, Muhammad, et al.
Publicado: (2021)

Polyphenols as Potential Inhibitors of SARS-CoV-2 RNA Dependent RNA Polymerase (RdRp)
por: Wu, Yifei, et al.
Publicado: (2021)

Allosteric activation of SARS-CoV-2 RdRp by remdesivir triphosphate and other phosphorylated nucleotides
por: Wang, Bing, et al.
Publicado: (2021)

Designing an effective therapeutic siRNA to silence RdRp gene of SARS-CoV-2
por: Shawan, Mohammad Mahfuz Ali Khan, et al.
Publicado: (2021)

Inhibition of HEV Replication by FDA-Approved RdRp Inhibitors
por: Hooda, Preeti, et al.
Publicado: (2023)

Evaluation of potential anti-RNA-dependent RNA polymerase (RdRP) drugs against the newly emerged model of COVID-19 RdRP using computational methods
por: Poustforoosh, Alireza, et al.
Publicado: (2021)

SARS-CoV-2 RNA Dependent RNA polymerase (RdRp) – A drug repurposing study
por: Ahmad, Jamshaid, et al.
Publicado: (2020)

Different selection dynamics of S and RdRp between SARS-CoV-2 genomes with and without the dominant mutations
por: Koçhan, Necla, et al.
Publicado: (2021)

Real-time PCR Ct value in SARS-CoV-2 detection: RdRp or N gene?
por: Abbasi, Hamidreza, et al.
Publicado: (2021)

Hybridization chain reaction circuit-based electrochemiluminescent biosensor for SARS-cov-2 RdRp gene assay
por: Zhang, Kai, et al.
Publicado: (2022)

Identification of Polyphenol Derivatives as Novel SARS-CoV-2 and DENV Non-Nucleoside RdRp Inhibitors
por: Gao, Shenghua, et al.
Publicado: (2022)

Composition of naturally occurring compounds decreases activity of Omicron and SARS-CoV-2 RdRp complex
por: Goc, Anna, et al.
Publicado: (2022)

Design, synthesis, docking, and biochemical characterization of non-nucleoside SARS-CoV-2 RdRp inhibitors
por: Brindani, Nicoletta, et al.
Publicado: (2023)

RdRp inhibitors and COVID-19: Is molnupiravir a good option?
por: Hashemian, Seyed Mohammad Reza, et al.
Publicado: (2022)

An Efficient Modern Strategy to Screen Drug Candidates Targeting RdRp of SARS-CoV-2 With Potentially High Selectivity and Specificity
por: Zhang, Haiping, et al.
Publicado: (2022)

Targeting 3CLpro and SARS-CoV-2 RdRp by Amphimedon sp. Metabolites: A Computational Study
por: Shady, Nourhan Hisham, et al.
Publicado: (2021)

Development of colorimetric sensors based on gold nanoparticles for SARS-CoV-2 RdRp, E and S genes detection
por: Rodríguez Díaz, Ciro, et al.
Publicado: (2022)

Effectiveness of Remdesivir in Comparison with Five Approved Antiviral Drugs for Inhibition of RdRp in Combat with SARS-CoV-2
por: Mahdian, Soodeh, et al.
Publicado: (2022)

Potential RNA-dependent RNA polymerase (RdRp) inhibitors as prospective drug candidates for SARS-CoV-2
por: Bekheit, Mohamed S., et al.
Publicado: (2023)

A duplex-specific nuclease based electrochemical biosensor for the assay of SARS-CoV-2 RdRp RNA
por: Zhou, Ke, et al.
Publicado: (2023)

Multiplex real-time RT-PCR method for the diagnosis of SARS-CoV-2 by targeting viral N, RdRP and human RP genes
por: Tombuloglu, Huseyin, et al.
Publicado: (2022)

Antiviral Protection via RdRP-Mediated Stable Activation of Innate Immunity
por: Painter, Meghan M., et al.
Publicado: (2015)

RdRp-based sensitive taxonomic classification of RNA viruses for metagenomic data
por: Tang, Xubo, et al.
Publicado: (2022)

High-throughput rational design of the remdesivir binding site in the RdRp of SARS-CoV-2: implications for potential resistance
por: Padhi, Aditya K., et al.
Publicado: (2020)

Variant Prediction by Analyzing RdRp/S Gene Double or Low Amplification Pattern in Allplex SARS-CoV-2 Assay
por: So, Min-Kyung, et al.
Publicado: (2021)

Molecular modelling and simulation techniques to investigate the effects of fungal metabolites on the SARS-CoV-2 RdRp protein inhibition
por: Muddapur, Uday M., et al.
Publicado: (2022)

Withania somnifera phytochemicals possess SARS-CoV-2 RdRp and human TMPRSS2 protein binding potential
por: Prajapati, Kumari Sunita, et al.
Publicado: (2022)

Linoleic acid binds to SARS-CoV-2 RdRp and represses replication of seasonal human coronavirus OC43
por: Goc, Anna, et al.
Publicado: (2022)

Analysis of the codon usage pattern of the RdRP gene of mycovirus infecting Aspergillus spp.
por: Je, Mikyung, et al.
Publicado: (2019)

Targeting the RdRp of Emerging RNA Viruses: The Structure-Based Drug Design Challenge
por: Picarazzi, Francesca, et al.
Publicado: (2020)

RNA-dependent RNA polymerase (RdRp) natural antiviral inhibitors: a review
por: Leite, Daniela Regina Buch, et al.
Publicado: (2022)

Azafluorene derivatives as inhibitors of SARS CoV-2 RdRp: Synthesis, physicochemical, quantum chemical, modeling and molecular docking analysis
por: Venkateshan, M., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_mvcsuhjilv401ehhmadeeknm4o