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Pharmacological Activity of Matrine in Inhibiting Colon Cancer Cells VM Formation, Proliferation, and Invasion by Downregulating Claudin-9 Mediated EMT Process and MAPK Signaling Pathway

PURPOSE: Matrine (Mat), the main active ingredient of traditional Chinese herbal plant Sophora flavescens Ait, has significant antitumor effects, but its pharmacological mechanism on colon cancer (CC) remains unclear. This study aimed to investigate the therapeutic effect of Mat on CC as well as the...

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Detalles Bibliográficos
Autores principales: Du, Qiu, Lin, Yingda, Ding, Changping, Wu, Ling, Xu, Yuan, Feng, Qingling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504061/
https://www.ncbi.nlm.nih.gov/pubmed/37719361
http://dx.doi.org/10.2147/DDDT.S417077