Adverse outcome pathway for pregnane X receptor-induced hypercholesterolemia

Pharmaceuticals and environmental contaminants contribute to hypercholesterolemia. Several chemicals known to cause hypercholesterolemia, activate pregnane X receptor (PXR). PXR is a nuclear receptor, classically identified as a sensor of chemical environment and regulator of detoxification processe...

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Detalles Bibliográficos
Autores principales: Itkonen, Anna, Hakkola, Jukka, Rysä, Jaana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504106/
https://www.ncbi.nlm.nih.gov/pubmed/37642746
http://dx.doi.org/10.1007/s00204-023-03575-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504106/
https://www.ncbi.nlm.nih.gov/pubmed/37642746
http://dx.doi.org/10.1007/s00204-023-03575-4

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