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Adverse outcome pathway for pregnane X receptor-induced hypercholesterolemia

Pharmaceuticals and environmental contaminants contribute to hypercholesterolemia. Several chemicals known to cause hypercholesterolemia, activate pregnane X receptor (PXR). PXR is a nuclear receptor, classically identified as a sensor of chemical environment and regulator of detoxification processe...

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Detalles Bibliográficos
Autores principales:	Itkonen, Anna, Hakkola, Jukka, Rysä, Jaana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2023
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504106/ https://www.ncbi.nlm.nih.gov/pubmed/37642746 http://dx.doi.org/10.1007/s00204-023-03575-4

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