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Mechanism of outer membrane destabilization by global reduction of protein content

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The outer membrane (OM) of Gram-negative bacteria such as Escherichia coli is an asymmetric bilayer with the glycolipid lipopolysaccharide (LPS) in the outer leaflet and glycerophospholipids in the inner. Nearly all integral OM proteins (OMPs) have a characteristic β-barrel fold and are assembled in...

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Detalles Bibliográficos
Autores principales:	Mikheyeva, Irina V., Sun, Jiawei, Huang, Kerwyn Casey, Silhavy, Thomas J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504340/ https://www.ncbi.nlm.nih.gov/pubmed/37714857 http://dx.doi.org/10.1038/s41467-023-40396-6

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