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Novel insights for a nonlinear deterministic-stochastic class of fractional-order Lassa fever model with varying kernels
Lassa fever is a hemorrhagic virus infection that is usually spread by rodents. It is a fatal infection that is prevalent in certain West African countries. We created an analytical deterministic-stochastic framework for the epidemics of Lassa fever employing a collection of ordinary differential eq...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504352/ https://www.ncbi.nlm.nih.gov/pubmed/37714907 http://dx.doi.org/10.1038/s41598-023-42106-0 |
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author | Rashid, Saima Karim, Shazia Akgül, Ali Bariq, Abdul Elagan, S. K. |
author_facet | Rashid, Saima Karim, Shazia Akgül, Ali Bariq, Abdul Elagan, S. K. |
author_sort | Rashid, Saima |
collection | PubMed |
description | Lassa fever is a hemorrhagic virus infection that is usually spread by rodents. It is a fatal infection that is prevalent in certain West African countries. We created an analytical deterministic-stochastic framework for the epidemics of Lassa fever employing a collection of ordinary differential equations with nonlinear solutions to identify the influence of propagation processes on infected development in individuals and rodents, which include channels that are commonly overlooked, such as ecological emergent and aerosol pathways. The findings shed light on the role of both immediate and subsequent infectiousness via the power law, exponential decay and generalized Mittag-Leffler kernels. The scenario involves the presence of a steady state and an endemic equilibrium regardless of the fundamental reproduction number, [Formula: see text] , making Lassa fever influence challenging and dependent on the severity of the initial sub-populations. Meanwhile, we demonstrate that the stochastic structure has an exclusive global positive solution via a positive starting point. The stochastic Lyapunov candidate approach is subsequently employed to determine sufficient requirements for the existence and uniqueness of an ergodic stationary distribution of non-negative stochastic simulation approaches. We acquire the particular configuration of the random perturbation associated with the model’s equilibrium [Formula: see text] according to identical environments as the presence of a stationary distribution. Ultimately, modeling techniques are used to verify the mathematical conclusions. Our fractional and stochastic findings exhibit that when all modes of transmission are included, the impact of Lassa fever disease increases. The majority of single dissemination pathways are less detrimental with fractional findings; however, when combined with additional spread pathways, they boost the Lassa fever stress. |
format | Online Article Text |
id | pubmed-10504352 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-105043522023-09-17 Novel insights for a nonlinear deterministic-stochastic class of fractional-order Lassa fever model with varying kernels Rashid, Saima Karim, Shazia Akgül, Ali Bariq, Abdul Elagan, S. K. Sci Rep Article Lassa fever is a hemorrhagic virus infection that is usually spread by rodents. It is a fatal infection that is prevalent in certain West African countries. We created an analytical deterministic-stochastic framework for the epidemics of Lassa fever employing a collection of ordinary differential equations with nonlinear solutions to identify the influence of propagation processes on infected development in individuals and rodents, which include channels that are commonly overlooked, such as ecological emergent and aerosol pathways. The findings shed light on the role of both immediate and subsequent infectiousness via the power law, exponential decay and generalized Mittag-Leffler kernels. The scenario involves the presence of a steady state and an endemic equilibrium regardless of the fundamental reproduction number, [Formula: see text] , making Lassa fever influence challenging and dependent on the severity of the initial sub-populations. Meanwhile, we demonstrate that the stochastic structure has an exclusive global positive solution via a positive starting point. The stochastic Lyapunov candidate approach is subsequently employed to determine sufficient requirements for the existence and uniqueness of an ergodic stationary distribution of non-negative stochastic simulation approaches. We acquire the particular configuration of the random perturbation associated with the model’s equilibrium [Formula: see text] according to identical environments as the presence of a stationary distribution. Ultimately, modeling techniques are used to verify the mathematical conclusions. Our fractional and stochastic findings exhibit that when all modes of transmission are included, the impact of Lassa fever disease increases. The majority of single dissemination pathways are less detrimental with fractional findings; however, when combined with additional spread pathways, they boost the Lassa fever stress. Nature Publishing Group UK 2023-09-15 /pmc/articles/PMC10504352/ /pubmed/37714907 http://dx.doi.org/10.1038/s41598-023-42106-0 Text en © The Author(s) 2023, corrected publication 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Rashid, Saima Karim, Shazia Akgül, Ali Bariq, Abdul Elagan, S. K. Novel insights for a nonlinear deterministic-stochastic class of fractional-order Lassa fever model with varying kernels |
title | Novel insights for a nonlinear deterministic-stochastic class of fractional-order Lassa fever model with varying kernels |
title_full | Novel insights for a nonlinear deterministic-stochastic class of fractional-order Lassa fever model with varying kernels |
title_fullStr | Novel insights for a nonlinear deterministic-stochastic class of fractional-order Lassa fever model with varying kernels |
title_full_unstemmed | Novel insights for a nonlinear deterministic-stochastic class of fractional-order Lassa fever model with varying kernels |
title_short | Novel insights for a nonlinear deterministic-stochastic class of fractional-order Lassa fever model with varying kernels |
title_sort | novel insights for a nonlinear deterministic-stochastic class of fractional-order lassa fever model with varying kernels |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504352/ https://www.ncbi.nlm.nih.gov/pubmed/37714907 http://dx.doi.org/10.1038/s41598-023-42106-0 |
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