Human skeletal muscle tissue chip autonomous payload reveals changes in fiber type and metabolic gene expression due to spaceflight

Microphysiological systems provide the opportunity to model accelerated changes at the human tissue level in the extreme space environment. Spaceflight-induced muscle atrophy experienced by astronauts shares similar physiological changes to muscle wasting in older adults, known as sarcopenia. These...

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Detalles Bibliográficos
Autores principales: Parafati, Maddalena, Giza, Shelby, Shenoy, Tushar S., Mojica-Santiago, Jorge A., Hopf, Meghan, Malany, Legrand K., Platt, Don, Moore, Isabel, Jacobs, Zachary A., Kuehl, Paul, Rexroat, Jason, Barnett, Gentry, Schmidt, Christine E., McLamb, William T., Clements, Twyman, Coen, Paul M., Malany, Siobhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504373/
https://www.ncbi.nlm.nih.gov/pubmed/37714852
http://dx.doi.org/10.1038/s41526-023-00322-y

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