Cargando…

METTL3‐mediated N6‐methyladenosine exacerbates ferroptosis via m6A‐IGF2BP2‐dependent mitochondrial metabolic reprogramming in sepsis‐induced acute lung injury

Neutrophil extracellular traps (NETs), released by polymorphonuclear neutrophils (PMNs), exert a robust antimicrobial function in infectious diseases such as sepsis. NETs also contribute to the pathogenesis and exacerbation of sepsis. Although the lung is highly vulnerable to infections, few studies...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Hao, Wu, Dan, Wang, Yanghanzhao, Guo, Kefang, Spencer, Charles B., Ortoga, Lilibeth, Qu, Mengdi, Shi, Yuxin, Shao, Yuwen, Wang, Zhiping, Cata, Juan P., Miao, Changhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504453/ https://www.ncbi.nlm.nih.gov/pubmed/37715457 http://dx.doi.org/10.1002/ctm2.1389

Ejemplares similares

Neutrophil extracellular traps mediate m(6)A modification and regulates sepsis-associated acute lung injury by activating ferroptosis in alveolar epithelial cells
por: Zhang, Hao, et al.
Publicado: (2022)

Neutrophil extracellular traps-triggered impaired autophagic flux via METTL3 underlies sepsis-associated acute lung injury
por: Qu, Mengdi, et al.
Publicado: (2022)

IGF2BP3 is an essential N(6)-methyladenosine biotarget for suppressing ferroptosis in lung adenocarcinoma cells
por: Xu, Xin, et al.
Publicado: (2022)

IGF2BP2 regulates DANCR by serving as an N6-methyladenosine reader
por: Hu, Xiaoge, et al.
Publicado: (2019)

N(6)-methyladenosine (m(6)A) methyltransferase METTL3 regulates sepsis-induced myocardial injury through IGF2BP1/HDAC4 dependent manner
por: Shen, Hao, et al.
Publicado: (2022)

N6-Methyladenosine Methyltransferase METTL3 Promotes Angiogenesis and Atherosclerosis by Upregulating the JAK2/STAT3 Pathway via m6A Reader IGF2BP1
por: Dong, Guo, et al.
Publicado: (2021)

METTL3/IGF2BP3 axis inhibits tumor immune surveillance by upregulating N(6)-methyladenosine modification of PD-L1 mRNA in breast cancer
por: Wan, Weijun, et al.
Publicado: (2022)

Solution structure of the RNA recognition domain of METTL3-METTL14 N(6)-methyladenosine methyltransferase
por: Huang, Jinbo, et al.
Publicado: (2018)

Recognition of RNA N(6)-methyladenosine by IGF2BP Proteins Enhances mRNA Stability and Translation
por: Huang, Huilin, et al.
Publicado: (2018)

N (6)-methyladenosine modification and METTL3 modulate enterovirus 71 replication
por: Hao, Haojie, et al.
Publicado: (2019)

RNA N6-methyladenosine reader IGF2BP3 regulates cell cycle and angiogenesis in colon cancer
por: Yang, Zhou, et al.
Publicado: (2020)

IGF2BP2 Regulates MALAT1 by Serving as an N6-Methyladenosine Reader to Promote NSCLC Proliferation
por: Han, Le, et al.
Publicado: (2022)

RNA N6-methyladenosine reader IGF2BP3 interacts with MYCN and facilitates neuroblastoma cell proliferation
por: Zhu, Kai, et al.
Publicado: (2023)

N(6)-methyladenosine reader IGF2BP3 as a prognostic Biomarker contribute to malignant progression of glioma
por: Zheng, Xin, et al.
Publicado: (2023)

Multi-omics analysis of N6-methyladenosine reader IGF2BP3 as a promising biomarker in pan-cancer
por: Chen, Pin, et al.
Publicado: (2023)

N(6)-methyladenosine (m(6)A) reader IGF2BP2 promotes gastric cancer progression via targeting SIRT1
por: Zhang, Zili, et al.
Publicado: (2022)

N(6)-methyladenosine (m(6)A) reader IGF2BP1 facilitates clear-cell renal cell carcinoma aerobic glycolysis
por: Yuan, Bao, et al.
Publicado: (2023)

Exploration of N6-Methyladenosine Profiles of mRNAs and the Function of METTL3 in Atherosclerosis
por: Zhou, Yaqing, et al.
Publicado: (2022)

METTL3 facilitates tumor progression via an m(6)A-IGF2BP2-dependent mechanism in colorectal carcinoma
por: Li, Ting, et al.
Publicado: (2019)

Neutrophil, neutrophil extracellular traps and endothelial cell dysfunction in sepsis
por: Zhang, Hao, et al.
Publicado: (2023)

Connecting N6‐methyladenosine modification to ferroptosis resistance in hepatoblastoma
por: Peng, Wan‐Xin, et al.
Publicado: (2022)

MYC-activated RNA N6-methyladenosine reader IGF2BP3 promotes cell proliferation and metastasis in nasopharyngeal carcinoma
por: Du, Mingyu, et al.
Publicado: (2022)

N6-methyladenosine modified LINC00901 promotes pancreatic cancer progression through IGF2BP2/MYC axis
por: Peng, Wan-Xin, et al.
Publicado: (2022)

The RNA N6-Methyladenosine Methyltransferase METTL3 Promotes the Progression of Kidney Cancer via N6-Methyladenosine-Dependent Translational Enhancement of ABCD1
por: Shi, Yue, et al.
Publicado: (2021)

METTL14 Facilitates the Metastasis of Pancreatic Carcinoma by Stabilizing LINC00941 in an m6A-IGF2BP2-Dependent Manner
por: Lu, Jiawei, et al.
Publicado: (2023)

METTL3/IGF2BP2 axis affects the progression of colorectal cancer by regulating m6A modification of STAG3
por: Yi, Jianmei, et al.
Publicado: (2023)

The N(6)-Methyladenosine mRNA Methylase METTL3 Controls Cardiac Homeostasis and Hypertrophy
por: Dorn, Lisa E., et al.
Publicado: (2019)

Multifaceted Roles of the N(6)-Methyladenosine RNA Methyltransferase METTL3 in Cancer and Immune Microenvironment
por: Hu, Chenxi, et al.
Publicado: (2022)

The N(6)-methyladenosine methyltransferase METTL16 enables erythropoiesis through safeguarding genome integrity
por: Yoshinaga, Masanori, et al.
Publicado: (2022)

CircPTPRA blocks the recognition of RNA N(6)-methyladenosine through interacting with IGF2BP1 to suppress bladder cancer progression
por: Xie, Fei, et al.
Publicado: (2021)

Abnormal Expression of N6-Methyladenosine RNA Methylation Regulator IGF2BP3 in Colon Cancer Predicts a Poor Prognosis
por: Wu, Tao, et al.
Publicado: (2022)

IGF2BP3 promotes progression of gallbladder carcinoma by stabilizing KLK5 mRNA in N(6)-methyladenosine-dependent binding
por: Zhang, Junzhe, et al.
Publicado: (2022)

METTL3-IGF2BP3-axis mediates the proliferation and migration of pancreatic cancer by regulating spermine synthase m6A modification
por: Guo, Zhenyun, et al.
Publicado: (2022)

N(6)-Methyladenosine METTL3 Modulates the Proliferation and Apoptosis of Lens Epithelial Cells in Diabetic Cataract
por: Yang, Jun, et al.
Publicado: (2020)

METTL3-mediated mRNA N(6)-methyladenosine is required for oocyte and follicle development in mice
por: Mu, Haiyuan, et al.
Publicado: (2021)

N-6-Methyladenosine in Vasoactive microRNAs during Hypoxia; A Novel Role for METTL4
por: van den Homberg, Daphne A. L., et al.
Publicado: (2022)

METTL3-Dependent N6-Methyladenosine Modification Programs Human Neural Progenitor Cell Proliferation
por: Zhao, Yuan, et al.
Publicado: (2023)

METTL14 is a chromatin regulator independent of its RNA N(6)-methyladenosine methyltransferase activity
por: Dou, Xiaoyang, et al.
Publicado: (2023)

The N(6)-methyladenosine (m(6)A)-forming enzyme METTL3 controls myeloid differentiation of normal and leukemia cells
por: Vu, Ly P., et al.
Publicado: (2017)

N(6)-methyladenosine (m(6)A) writer METTL3 accelerates the apoptosis of vascular endothelial cells in high glucose
por: Li, Zhenjin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_81744768t94eq478f9i2mj926a