The human leukemic oncogene MLL-AF4 promotes hyperplastic growth of hematopoietic tissues in Drosophila larvae

MLL-rearranged (MLL-r) leukemias are among the leukemic subtypes with poorest survival, and treatment options have barely improved over the last decades. Despite increasing molecular understanding of the mechanisms behind these hematopoietic malignancies, this knowledge has had poor translation into...

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Detalles Bibliográficos
Autores principales: Johannessen, Julie A., Formica, Miriam, Haukeland, Aina Louise C., Bråthen, Nora Rojahn, Al Outa, Amani, Aarsund, Miriam, Therrien, Marc, Enserink, Jorrit M., Knævelsrud, Helene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504488/
https://www.ncbi.nlm.nih.gov/pubmed/37720104
http://dx.doi.org/10.1016/j.isci.2023.107726

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