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1-deoxy-D-xylulose-5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding

The ESKAPE bacteria are the six highly virulent and antibiotic-resistant pathogens that require the most urgent attention for the development of novel antibiotics. Detailed knowledge of target proteins specific to bacteria is essential to develop novel treatment options. The methylerythritol-phospha...

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Detalles Bibliográficos
Autores principales:	Hamid, Rawia, Adam, Sebastian, Lacour, Antoine, Monjas, Leticia, Köhnke, Jesko, Hirsch, Anna K.H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504544/ https://www.ncbi.nlm.nih.gov/pubmed/37567475 http://dx.doi.org/10.1016/j.jbc.2023.105152

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