Identifying genetic regulatory variants that affect transcription factor activity

Genetic variants affecting gene expression levels in humans have been mapped in the Genotype-Tissue Expression (GTEx) project. Trans-acting variants impacting many genes simultaneously through a shared transcription factor (TF) are of particular interest. Here, we developed a generalized linear mode...

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Detalles Bibliográficos
Autores principales: Li, Xiaoting, Lappalainen, Tuuli, Bussemaker, Harmen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504674/
https://www.ncbi.nlm.nih.gov/pubmed/37719147
http://dx.doi.org/10.1016/j.xgen.2023.100382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504674/
https://www.ncbi.nlm.nih.gov/pubmed/37719147
http://dx.doi.org/10.1016/j.xgen.2023.100382

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