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Unraveling dynamically encoded latent transcriptomic patterns in pancreatic cancer cells by topic modeling

Building a comprehensive topic model has become an important research tool in single-cell genomics. With a topic model, we can decompose and ascertain distinctive cell topics shared across multiple cells, and the gene programs implicated by each topic can later serve as a predictive model in transla...

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Detalles Bibliográficos
Autores principales: Zhang, Yichen, Khalilitousi, Mohammadali (Sam), Park, Yongjin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504675/
https://www.ncbi.nlm.nih.gov/pubmed/37719139
http://dx.doi.org/10.1016/j.xgen.2023.100388

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