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Assessment of potentially inappropriate medication use among geriatric outpatients in the Slovak Republic

BACKGROUND: Potentially inappropriate medication (PIM) use is a highly prevalent problem among older people, making it challenging to improve patient safety. The aim of this study was to assess the use of PIMs among geriatric outpatients (OUTs) in the Slovak Republic according to the EU(7) PIM list...

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Autores principales: Kosirova, Stanislava, Urbankova, Jana, Klimas, Jan, Foltanova, Tatiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504736/
https://www.ncbi.nlm.nih.gov/pubmed/37715169
http://dx.doi.org/10.1186/s12877-023-04260-y
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author Kosirova, Stanislava
Urbankova, Jana
Klimas, Jan
Foltanova, Tatiana
author_facet Kosirova, Stanislava
Urbankova, Jana
Klimas, Jan
Foltanova, Tatiana
author_sort Kosirova, Stanislava
collection PubMed
description BACKGROUND: Potentially inappropriate medication (PIM) use is a highly prevalent problem among older people, making it challenging to improve patient safety. The aim of this study was to assess the use of PIMs among geriatric outpatients (OUTs) in the Slovak Republic according to the EU(7) PIM list and to identify the differences in PIM prescriptions among general practitioners (GPs), internists (INTs) and geriatricians (GERs). METHODS: In total, 449 patients (65 years and older) from 4 medical centres who were in the care of GPs (32.5%), INTs (22.7%) or GERs (44.8%) were included in this retrospective analysis. Data were collected from 1.12.2019–31.3.2020. PIMs were identified according to the EU(7) PIM list from patients’ records. PIM prescriptions by GPs, INTs and GERs were assessed. All obtained data were statistically analysed. RESULTS: Polypharmacy (68.8% of patients), and PIM use (73% of patients) were observed. The mean number of all prescribed drugs was 6.7 ± 0.2 drugs per day/patient. The mean number of prescribed PIMs was 1.7 ± 0.1 PIMs per day/patient. Drugs from Anatomical Therapeutic Chemical (ATC) classes C, N and A accounted for the greatest number of PIMs. Significantly higher numbers of prescribed drugs as well as PIMs were prescribed by GPs than INTs or GERs. There were 4.2 times higher odds of being prescribed PIMs by GPs than by GERs (p < 0.001). CONCLUSIONS: Polypharmacy and overprescription of PIMs were identified among geriatric patients in our study. We found a positive relationship between the number of prescribed drugs and PIMs. The lowest odds of being prescribed PIMs were observed among those who were in the care of a geriatrician. The absence of geriatricians and lack of information about PIMs among general practitioners leads to high rates of polypharmacy and overuse of potentially inappropriate medications in geriatric patients in the Slovak Republic. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12877-023-04260-y.
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spelling pubmed-105047362023-09-17 Assessment of potentially inappropriate medication use among geriatric outpatients in the Slovak Republic Kosirova, Stanislava Urbankova, Jana Klimas, Jan Foltanova, Tatiana BMC Geriatr Research BACKGROUND: Potentially inappropriate medication (PIM) use is a highly prevalent problem among older people, making it challenging to improve patient safety. The aim of this study was to assess the use of PIMs among geriatric outpatients (OUTs) in the Slovak Republic according to the EU(7) PIM list and to identify the differences in PIM prescriptions among general practitioners (GPs), internists (INTs) and geriatricians (GERs). METHODS: In total, 449 patients (65 years and older) from 4 medical centres who were in the care of GPs (32.5%), INTs (22.7%) or GERs (44.8%) were included in this retrospective analysis. Data were collected from 1.12.2019–31.3.2020. PIMs were identified according to the EU(7) PIM list from patients’ records. PIM prescriptions by GPs, INTs and GERs were assessed. All obtained data were statistically analysed. RESULTS: Polypharmacy (68.8% of patients), and PIM use (73% of patients) were observed. The mean number of all prescribed drugs was 6.7 ± 0.2 drugs per day/patient. The mean number of prescribed PIMs was 1.7 ± 0.1 PIMs per day/patient. Drugs from Anatomical Therapeutic Chemical (ATC) classes C, N and A accounted for the greatest number of PIMs. Significantly higher numbers of prescribed drugs as well as PIMs were prescribed by GPs than INTs or GERs. There were 4.2 times higher odds of being prescribed PIMs by GPs than by GERs (p < 0.001). CONCLUSIONS: Polypharmacy and overprescription of PIMs were identified among geriatric patients in our study. We found a positive relationship between the number of prescribed drugs and PIMs. The lowest odds of being prescribed PIMs were observed among those who were in the care of a geriatrician. The absence of geriatricians and lack of information about PIMs among general practitioners leads to high rates of polypharmacy and overuse of potentially inappropriate medications in geriatric patients in the Slovak Republic. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12877-023-04260-y. BioMed Central 2023-09-15 /pmc/articles/PMC10504736/ /pubmed/37715169 http://dx.doi.org/10.1186/s12877-023-04260-y Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Kosirova, Stanislava
Urbankova, Jana
Klimas, Jan
Foltanova, Tatiana
Assessment of potentially inappropriate medication use among geriatric outpatients in the Slovak Republic
title Assessment of potentially inappropriate medication use among geriatric outpatients in the Slovak Republic
title_full Assessment of potentially inappropriate medication use among geriatric outpatients in the Slovak Republic
title_fullStr Assessment of potentially inappropriate medication use among geriatric outpatients in the Slovak Republic
title_full_unstemmed Assessment of potentially inappropriate medication use among geriatric outpatients in the Slovak Republic
title_short Assessment of potentially inappropriate medication use among geriatric outpatients in the Slovak Republic
title_sort assessment of potentially inappropriate medication use among geriatric outpatients in the slovak republic
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504736/
https://www.ncbi.nlm.nih.gov/pubmed/37715169
http://dx.doi.org/10.1186/s12877-023-04260-y
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