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Disseminated Nocardia Brain Abscess Presenting as Primary Lung Cancer With Brain Metastasis
We present a challenging case of disseminated Nocardia brasiliensis infection manifesting as brain and skin abscesses. Nocardia is an important potential pathogen to consider in patients with a relevant travel history to endemic regions or atypical presentations, such as brain and skin abscesses. Ab...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504867/ https://www.ncbi.nlm.nih.gov/pubmed/37719483 http://dx.doi.org/10.7759/cureus.43631 |
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author | Silwal, Swechchha Mir, Mikael Boike, Sydney Bista, Karuna Yadav, Sumeet K Sheehy, Jessica Khan, Syed Anjum Gomez Urena, Eric O |
author_facet | Silwal, Swechchha Mir, Mikael Boike, Sydney Bista, Karuna Yadav, Sumeet K Sheehy, Jessica Khan, Syed Anjum Gomez Urena, Eric O |
author_sort | Silwal, Swechchha |
collection | PubMed |
description | We present a challenging case of disseminated Nocardia brasiliensis infection manifesting as brain and skin abscesses. Nocardia is an important potential pathogen to consider in patients with a relevant travel history to endemic regions or atypical presentations, such as brain and skin abscesses. About one-third of patients with Nocardia infections are immunocompetent, and their symptoms are nonspecific. This case shows the limitations of imaging studies in diagnosing Nocardia brain abscesses, as the patient’s non-magnetic resonance (MR) conditional pacemaker precluded MRI evaluation and led to a diagnostic challenge. Therefore, the patient’s initial evaluation was presumed to be primary lung cancer with brain metastasis. High clinical suspicion, imaging studies (especially MRI), and tissue biopsy are needed to diagnose this type of brain abscess in a timely manner to prevent further complications. |
format | Online Article Text |
id | pubmed-10504867 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-105048672023-09-17 Disseminated Nocardia Brain Abscess Presenting as Primary Lung Cancer With Brain Metastasis Silwal, Swechchha Mir, Mikael Boike, Sydney Bista, Karuna Yadav, Sumeet K Sheehy, Jessica Khan, Syed Anjum Gomez Urena, Eric O Cureus Radiology We present a challenging case of disseminated Nocardia brasiliensis infection manifesting as brain and skin abscesses. Nocardia is an important potential pathogen to consider in patients with a relevant travel history to endemic regions or atypical presentations, such as brain and skin abscesses. About one-third of patients with Nocardia infections are immunocompetent, and their symptoms are nonspecific. This case shows the limitations of imaging studies in diagnosing Nocardia brain abscesses, as the patient’s non-magnetic resonance (MR) conditional pacemaker precluded MRI evaluation and led to a diagnostic challenge. Therefore, the patient’s initial evaluation was presumed to be primary lung cancer with brain metastasis. High clinical suspicion, imaging studies (especially MRI), and tissue biopsy are needed to diagnose this type of brain abscess in a timely manner to prevent further complications. Cureus 2023-08-17 /pmc/articles/PMC10504867/ /pubmed/37719483 http://dx.doi.org/10.7759/cureus.43631 Text en Copyright © 2023, Silwal et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Radiology Silwal, Swechchha Mir, Mikael Boike, Sydney Bista, Karuna Yadav, Sumeet K Sheehy, Jessica Khan, Syed Anjum Gomez Urena, Eric O Disseminated Nocardia Brain Abscess Presenting as Primary Lung Cancer With Brain Metastasis |
title | Disseminated Nocardia Brain Abscess Presenting as Primary Lung Cancer With Brain Metastasis |
title_full | Disseminated Nocardia Brain Abscess Presenting as Primary Lung Cancer With Brain Metastasis |
title_fullStr | Disseminated Nocardia Brain Abscess Presenting as Primary Lung Cancer With Brain Metastasis |
title_full_unstemmed | Disseminated Nocardia Brain Abscess Presenting as Primary Lung Cancer With Brain Metastasis |
title_short | Disseminated Nocardia Brain Abscess Presenting as Primary Lung Cancer With Brain Metastasis |
title_sort | disseminated nocardia brain abscess presenting as primary lung cancer with brain metastasis |
topic | Radiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504867/ https://www.ncbi.nlm.nih.gov/pubmed/37719483 http://dx.doi.org/10.7759/cureus.43631 |
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