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Prognostic predictive value of intracranial pressure and cerebral oxygen metabolism monitoring in patients with spontaneous intracerebral hemorrhage

OBJECTIVE: Our study aimed to investigate the predictive value of intracranial pressure (ICP) and cerebral oxygen metabolism monitoring in the postoperative prognosis of patients with spontaneous intracerebral hemorrhage (SICH). METHODS: The clinical data of 55 patients with SICH treated by neurosur...

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Autores principales: Sun, Zhen, Liu, Jing, Dong, Shengpu, Duan, Xianglong, Xue, Fei, Miao, Xingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505100/
https://www.ncbi.nlm.nih.gov/pubmed/36029437
http://dx.doi.org/10.1007/s13760-022-02037-5
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author Sun, Zhen
Liu, Jing
Dong, Shengpu
Duan, Xianglong
Xue, Fei
Miao, Xingyu
author_facet Sun, Zhen
Liu, Jing
Dong, Shengpu
Duan, Xianglong
Xue, Fei
Miao, Xingyu
author_sort Sun, Zhen
collection PubMed
description OBJECTIVE: Our study aimed to investigate the predictive value of intracranial pressure (ICP) and cerebral oxygen metabolism monitoring in the postoperative prognosis of patients with spontaneous intracerebral hemorrhage (SICH). METHODS: The clinical data of 55 patients with SICH treated by neurosurgery were analyzed retrospectively. These patients were divided into two groups based on postoperative Glasgow Outcome Scale (GOS) scores, i.e., the poor prognosis group (GOS I-III) and the good prognosis group (GOS IV and V). Next, the ICP and cerebral oxygen metabolism indexes, such as brain temperature (BT), cerebral perfusion pressure (CPP), internal jugular venous oxygen saturation (SjvO(2)), and arterial partial pressure of carbon dioxide (PaCO(2)), were recorded after the operation. Further, the prognostic differences between the two groups were compared, and the predictive values were evaluated using the receiver operating characteristic curve (ROC) and area under the curve (AUC). RESULTS: The results showed that the average ICP and BT in the good prognosis group were lower than those in the poor prognosis group. However, the CPP and SjvO(2) in the good prognosis group were higher than those in the poor prognosis group. Moreover, the incidence of low PaCO(2) in the poor prognosis group was higher than that in the good prognosis group. CONCLUSIONS: Our results demonstrated that the average ICP, BT, CPP, SjvO(2), and arterial PaCO(2) may reflect the changes in brain function and cerebral blood flow, which are significantly correlated with the prognosis of patients. Further, our findings indicated that the combined postoperative ICP levels with cerebral oxygen metabolism indexes could guide clinical treatments and predict prognosis.
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spelling pubmed-105051002023-09-18 Prognostic predictive value of intracranial pressure and cerebral oxygen metabolism monitoring in patients with spontaneous intracerebral hemorrhage Sun, Zhen Liu, Jing Dong, Shengpu Duan, Xianglong Xue, Fei Miao, Xingyu Acta Neurol Belg Original Article OBJECTIVE: Our study aimed to investigate the predictive value of intracranial pressure (ICP) and cerebral oxygen metabolism monitoring in the postoperative prognosis of patients with spontaneous intracerebral hemorrhage (SICH). METHODS: The clinical data of 55 patients with SICH treated by neurosurgery were analyzed retrospectively. These patients were divided into two groups based on postoperative Glasgow Outcome Scale (GOS) scores, i.e., the poor prognosis group (GOS I-III) and the good prognosis group (GOS IV and V). Next, the ICP and cerebral oxygen metabolism indexes, such as brain temperature (BT), cerebral perfusion pressure (CPP), internal jugular venous oxygen saturation (SjvO(2)), and arterial partial pressure of carbon dioxide (PaCO(2)), were recorded after the operation. Further, the prognostic differences between the two groups were compared, and the predictive values were evaluated using the receiver operating characteristic curve (ROC) and area under the curve (AUC). RESULTS: The results showed that the average ICP and BT in the good prognosis group were lower than those in the poor prognosis group. However, the CPP and SjvO(2) in the good prognosis group were higher than those in the poor prognosis group. Moreover, the incidence of low PaCO(2) in the poor prognosis group was higher than that in the good prognosis group. CONCLUSIONS: Our results demonstrated that the average ICP, BT, CPP, SjvO(2), and arterial PaCO(2) may reflect the changes in brain function and cerebral blood flow, which are significantly correlated with the prognosis of patients. Further, our findings indicated that the combined postoperative ICP levels with cerebral oxygen metabolism indexes could guide clinical treatments and predict prognosis. Springer International Publishing 2022-08-27 2023 /pmc/articles/PMC10505100/ /pubmed/36029437 http://dx.doi.org/10.1007/s13760-022-02037-5 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Sun, Zhen
Liu, Jing
Dong, Shengpu
Duan, Xianglong
Xue, Fei
Miao, Xingyu
Prognostic predictive value of intracranial pressure and cerebral oxygen metabolism monitoring in patients with spontaneous intracerebral hemorrhage
title Prognostic predictive value of intracranial pressure and cerebral oxygen metabolism monitoring in patients with spontaneous intracerebral hemorrhage
title_full Prognostic predictive value of intracranial pressure and cerebral oxygen metabolism monitoring in patients with spontaneous intracerebral hemorrhage
title_fullStr Prognostic predictive value of intracranial pressure and cerebral oxygen metabolism monitoring in patients with spontaneous intracerebral hemorrhage
title_full_unstemmed Prognostic predictive value of intracranial pressure and cerebral oxygen metabolism monitoring in patients with spontaneous intracerebral hemorrhage
title_short Prognostic predictive value of intracranial pressure and cerebral oxygen metabolism monitoring in patients with spontaneous intracerebral hemorrhage
title_sort prognostic predictive value of intracranial pressure and cerebral oxygen metabolism monitoring in patients with spontaneous intracerebral hemorrhage
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505100/
https://www.ncbi.nlm.nih.gov/pubmed/36029437
http://dx.doi.org/10.1007/s13760-022-02037-5
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