Assessment of Drug–Drug Interaction Risk Between Intravenous Fentanyl and the Glecaprevir/Pibrentasvir Combination Regimen in Hepatitis C Patients Using Physiologically Based Pharmacokinetic Modeling and Simulations

INTRODUCTION: An unsafe injection practice is one of the major contributors to new hepatitis C virus (HCV) infections; thus, people who inject drugs are a key population to prioritize to achieve HCV elimination. The introduction of highly effective and well-tolerated pangenotypic direct-acting antiv...

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Detalles Bibliográficos
Autores principales: Mukherjee, Dwaipayan, Collins, Michelle, Dylla, Douglas E., Kaur, Jatinder, Semizarov, Dimitri, Martinez, Anthony, Conway, Brian, Khan, Tipu, Mostafa, Nael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505123/
https://www.ncbi.nlm.nih.gov/pubmed/37470926
http://dx.doi.org/10.1007/s40121-023-00830-0

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