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A cross-cohort computational framework to trace tumor tissue-of-origin based on RNA sequencing
Carcinoma of unknown primary (CUP) is a type of metastatic cancer with tissue-of-origin (TOO) unidentifiable by traditional methods. CUP patients typically have poor prognosis but therapy targeting the original cancer tissue can significantly improve patients’ prognosis. Thus, it’s critical to devel...
Autores principales: | He, Binsheng, Sun, Hongmei, Bao, Meihua, Li, Haigang, He, Jianjun, Tian, Geng, Wang, Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505149/ https://www.ncbi.nlm.nih.gov/pubmed/37717102 http://dx.doi.org/10.1038/s41598-023-42465-8 |
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