Cargando…

Unraveling the link between PTBP1 and severe asthma through machine learning and association rule mining method

Severe asthma is a chronic inflammatory airway disease with great therapeutic challenges. Understanding the genetic and molecular mechanisms of severe asthma may help identify therapeutic strategies for this complex condition. RNA expression data were analyzed using a combination of artificial intel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pirmoradi, Saeed, Hosseiniyan Khatibi, Seyed Mahdi, Zununi Vahed, Sepideh, Homaei Rad, Hamed, Khamaneh, Amir Mahdi, Akbarpour, Zahra, Seyedrezazadeh, Ensiyeh, Teshnehlab, Mohammad, Chapman, Kenneth R., Ansarin, Khalil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505163/ https://www.ncbi.nlm.nih.gov/pubmed/37717070 http://dx.doi.org/10.1038/s41598-023-42581-5

Ejemplares similares

Uncovering key molecular mechanisms in the early and late-stage of papillary thyroid carcinoma using association rule mining algorithm
por: Hosseiniyan Khatibi, Seyed Mahdi, et al.
Publicado: (2023)

Key therapeutic targets implicated at the early stage of hepatocellular carcinoma identified through machine-learning approaches
por: Hosseiniyan Khatibi, Seyed Mahdi, et al.
Publicado: (2023)

Panels of mRNAs and miRNAs for decoding molecular mechanisms of Renal Cell Carcinoma (RCC) subtypes utilizing Artificial Intelligence approaches
por: Hosseiniyan Khatibi, Seyed Mahdi, et al.
Publicado: (2022)

Targeting chronic COVID-19 lung injury; Tofacitinib can be used against tissue-resident memory T cells
por: Zununi Vahed, Sepideh, et al.
Publicado: (2022)

Host Serine Proteases: A Potential Targeted Therapy for COVID-19 and Influenza
por: Rahbar Saadat, Yalda, et al.
Publicado: (2021)

Vascular Calcification: An Important Understanding in Nephrology
por: Zununi Vahed, Sepideh, et al.
Publicado: (2020)

The Battle of Probiotics and Their Derivatives Against Biofilms
por: Barzegari, Abolfazl, et al.
Publicado: (2020)

Stem cell-derived biofactors fight against coronavirus infection
por: Ardalan, Mohammadreza, et al.
Publicado: (2021)

Targeting Mitochondrial Biogenesis with Polyphenol Compounds
por: Chodari, Leila, et al.
Publicado: (2021)

Terminalia Catappa Extract (TCE) Reduces Proliferation of Lung and Breast Cancer Cell by Modulating miR-21 and miR-34a Expressions
por: Zarredar, Habib, et al.
Publicado: (2021)

Application of Advanced Nanomaterials for Kidney Failure Treatment and Regeneration
por: Eftekhari, Aziz, et al.
Publicado: (2021)

Polymorphism (-499C/G) in DDAH2 promoter may act as a protective factor for metabolic syndrome: A case-control study in Azar-Cohort population
por: Faramarzi, Elnaz, et al.
Publicado: (2021)

The effect of Fingolimod on patients with moderate to severe COVID‐19
por: Teymouri, Soheil, et al.
Publicado: (2022)

Association of NOS3-c.894G>T transversion with susceptibility to metabolic syndrome in Azar-cohort population: A case-control study and in silico analysis of the SNP molecular effects
por: Seyedrezazadeh, Ensiyeh, et al.
Publicado: (2021)

Upregulation of miR-142 in papillary thyroid carcinoma tissues: a report based on in silico and in vitro analysis
por: Valizadeh, Sepehr, et al.
Publicado: (2022)

Investigation and confirmation of differentially expressed miRNAs, as well as target gene prediction in papillary thyroid cancer, with a special emphasis on the autophagy signaling pathway
por: Zehtabi, Mojtaba, et al.
Publicado: (2022)

Dietary Factors and Risk of Chronic Obstructive Pulmonary Disease: a Systemic Review and Meta-Analysis
por: Seyedrezazadeh, Ensiyeh, et al.
Publicado: (2019)

Pharmacogenetics and drug-induced nephrotoxicity in renal transplant recipients
por: Zununi Vahed, Sepideh, et al.
Publicado: (2015)

Immunosuppressant Management in Renal Transplant Patients with COVID-19
por: Ahmadian, Elham, et al.
Publicado: (2021)

Biodegradation of Para Amino Acetanilide by Halomonas sp. TBZ3
por: Hajizadeh, Nader, et al.
Publicado: (2015)

PTBP1 and PTBP2 impaired autoregulation of SRSF3 in cancer cells
por: Guo, Jihua, et al.
Publicado: (2015)

An update to DNA ladder assay for apoptosis detection
por: Rahbar Saadat, Yalda, et al.
Publicado: (2015)

A microRNA isolation method from clinical samples
por: Zununi Vahed, Sepideh, et al.
Publicado: (2016)

Expression Levels of miR-30c and miR-186 in Adult Patients with Membranous Glomerulonephritis and Focal Segmental Glomerulosclerosis
por: Hejazian, Seyyedeh Mina, et al.
Publicado: (2020)

The Association of Sleep Quality and Vitamin D Levels in Hemodialysis Patients
por: Hejazian, Seyyedeh Mina, et al.
Publicado: (2021)

Economic Burden of Asthma in Northwest Iran
por: Seyedrezazadeh, Ensiyeh, et al.
Publicado: (2023)

COVID-19 infection: an overview on cytokine storm and related interventions
por: Montazersaheb, Soheila, et al.
Publicado: (2022)

Psd-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2
por: Zheng, Sika, et al.
Publicado: (2012)

Multiple determinants of splicing repression activity in the polypyrimidine tract binding proteins, PTBP1 and PTBP2
por: Keppetipola, Niroshika M., et al.
Publicado: (2016)

Association of the Toll-like receptor 4 and NOX4 gene and protein levels in asthmatic patients with metabolic syndrome: A case–control study
por: Ghoushouni, Sevda, et al.
Publicado: (2023)

Altered levels of immune-regulatory microRNAs in plasma samples of patients with lupus nephritis
por: Zununi Vahed, Sepideh, et al.
Publicado: (2018)

Vitamin D Receptor and Vitamin D Binding Protein Gene Polymorphisms Are Associated with Renal Allograft Outcome
por: Zununi Vahed, Sepideh, et al.
Publicado: (2021)

TTP-like syndrome and its relationship with complement activation in critically ill patients with COVID-19: A cross-sectional study
por: Ardalan, Mohammadreza, et al.
Publicado: (2023)

Factors associated with the reproductive health of women living with HIV in Iran
por: Shikhansari, Sepideh, et al.
Publicado: (2021)

Evidences from a Systematic Review and Meta-Analysis Unveil the Role of MiRNA Polymorphisms in the Predisposition to Female Neoplasms
por: Bastami, Milad, et al.
Publicado: (2019)

Klotho and Renal Fibrosis
por: Zununi Vahed, Sepide, et al.
Publicado: (2013)

Polypyrimidine tract binding proteins PTBP1 and PTBP2 interact with distinct proteins under splicing conditions
por: Pina, Jeffrey M., et al.
Publicado: (2022)

Association of proinflammatory genes expression with serum interleukin 1β and free fatty acids in metabolically healthy and unhealthy abdominally obese individuals: a case-control study
por: Amiri, Parichehr, et al.
Publicado: (2019)

Action Rules Mining
por: Dardzinska, Agnieszka
Publicado: (2013)

SON drives oncogenic RNA splicing in glioblastoma by regulating PTBP1/PTBP2 switching and RBFOX2 activity
por: Kim, Jung-Hyun, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_lmsnuamvsh07k5d2avvdfjq6s4