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Delayed Presentation of Antipsychotic Withdrawal Tardive Dyskinesia: A Case Report

Tardive dyskinesia (TD) is an iatrogenic cause that occurs after prolonged use of antipsychotic and other dopamine-related medications and is described as repetitive, involuntary movement of muscles in the body. This case report focuses on an 80-year-old man who presented with a medical history enco...

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Autores principales: Solanki, Siddhant, Velugoti, Lakshmi Sai Deepak Reddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505356/
https://www.ncbi.nlm.nih.gov/pubmed/37724196
http://dx.doi.org/10.7759/cureus.43693
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author Solanki, Siddhant
Velugoti, Lakshmi Sai Deepak Reddy
author_facet Solanki, Siddhant
Velugoti, Lakshmi Sai Deepak Reddy
author_sort Solanki, Siddhant
collection PubMed
description Tardive dyskinesia (TD) is an iatrogenic cause that occurs after prolonged use of antipsychotic and other dopamine-related medications and is described as repetitive, involuntary movement of muscles in the body. This case report focuses on an 80-year-old man who presented with a medical history encompassing dementia, bilateral blindness, glaucoma, hearing loss, hypertension, and hypercholesterolemia. He visited the clinic with a complaint of experiencing visual hallucinations. Investigations, including a CT head and EEG, revealed normal results, and Risperidone was prescribed. In the subsequent visit, Risperidone was prescribed again with Quetiapine and then replaced with valproate because of no change in symptoms and medication non-adherence. Over time, the patient felt better but started to have orofacial tremors after three months of discontinuing antipsychotic medications. For the orofacial tremors, the patient was prescribed Duetetrabenazine and asked for a follow-up visit. Early recognition and treatment of TD would be beneficial for these patients, and when prescribing, it's important to be aware that they may lead to delayed onset of TD.
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spelling pubmed-105053562023-09-18 Delayed Presentation of Antipsychotic Withdrawal Tardive Dyskinesia: A Case Report Solanki, Siddhant Velugoti, Lakshmi Sai Deepak Reddy Cureus Neurology Tardive dyskinesia (TD) is an iatrogenic cause that occurs after prolonged use of antipsychotic and other dopamine-related medications and is described as repetitive, involuntary movement of muscles in the body. This case report focuses on an 80-year-old man who presented with a medical history encompassing dementia, bilateral blindness, glaucoma, hearing loss, hypertension, and hypercholesterolemia. He visited the clinic with a complaint of experiencing visual hallucinations. Investigations, including a CT head and EEG, revealed normal results, and Risperidone was prescribed. In the subsequent visit, Risperidone was prescribed again with Quetiapine and then replaced with valproate because of no change in symptoms and medication non-adherence. Over time, the patient felt better but started to have orofacial tremors after three months of discontinuing antipsychotic medications. For the orofacial tremors, the patient was prescribed Duetetrabenazine and asked for a follow-up visit. Early recognition and treatment of TD would be beneficial for these patients, and when prescribing, it's important to be aware that they may lead to delayed onset of TD. Cureus 2023-08-18 /pmc/articles/PMC10505356/ /pubmed/37724196 http://dx.doi.org/10.7759/cureus.43693 Text en Copyright © 2023, Solanki et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurology
Solanki, Siddhant
Velugoti, Lakshmi Sai Deepak Reddy
Delayed Presentation of Antipsychotic Withdrawal Tardive Dyskinesia: A Case Report
title Delayed Presentation of Antipsychotic Withdrawal Tardive Dyskinesia: A Case Report
title_full Delayed Presentation of Antipsychotic Withdrawal Tardive Dyskinesia: A Case Report
title_fullStr Delayed Presentation of Antipsychotic Withdrawal Tardive Dyskinesia: A Case Report
title_full_unstemmed Delayed Presentation of Antipsychotic Withdrawal Tardive Dyskinesia: A Case Report
title_short Delayed Presentation of Antipsychotic Withdrawal Tardive Dyskinesia: A Case Report
title_sort delayed presentation of antipsychotic withdrawal tardive dyskinesia: a case report
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505356/
https://www.ncbi.nlm.nih.gov/pubmed/37724196
http://dx.doi.org/10.7759/cureus.43693
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