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A Rare Case of Sinonasal Ewing Sarcoma With Radiologic-Pathologic Correlation

An 89-year-old male presented with syncope and worsening difficulty in breathing through the left nostril. Computed tomography demonstrated a tumor in the anterior ethmoid air cells and maxillary sinus, which extended into the frontal lobe. Magnetic resonance imaging similarly demonstrated an aggres...

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Autores principales: Worthy, Jennifer, Ganguli, Malika P, Kile, Mahlon R, Satei, Alexander M, Mills, Nicholas D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505484/
https://www.ncbi.nlm.nih.gov/pubmed/37724222
http://dx.doi.org/10.7759/cureus.43708
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author Worthy, Jennifer
Ganguli, Malika P
Kile, Mahlon R
Satei, Alexander M
Mills, Nicholas D
author_facet Worthy, Jennifer
Ganguli, Malika P
Kile, Mahlon R
Satei, Alexander M
Mills, Nicholas D
author_sort Worthy, Jennifer
collection PubMed
description An 89-year-old male presented with syncope and worsening difficulty in breathing through the left nostril. Computed tomography demonstrated a tumor in the anterior ethmoid air cells and maxillary sinus, which extended into the frontal lobe. Magnetic resonance imaging similarly demonstrated an aggressive lesion. This mass was difficult to differentiate from more commonly seen lesions at this location such as an esthesioneuroblastoma or nasopharyngeal carcinoma. Direct visualization, biopsy, and subsequent pathologic analysis eventually confirmed the diagnosis of malignant Ewing sarcoma (EWS). Our case explores the radiological findings of EWS originating from the ethmoid sinus, compares EWS with other common carcinomas in the same location, confirms the diagnosis through pathological correlation, and investigates the prognosis and treatment of these lesions. This case highlights the importance of a multidisciplinary approach to diagnose EWS when it occurs in an atypical location. The clinical team relied on input from the radiology, surgery, ENT, neurology, and pathology departments to make an accurate diagnosis and plan treatment for this aggressive tumor.
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spelling pubmed-105054842023-09-18 A Rare Case of Sinonasal Ewing Sarcoma With Radiologic-Pathologic Correlation Worthy, Jennifer Ganguli, Malika P Kile, Mahlon R Satei, Alexander M Mills, Nicholas D Cureus Pathology An 89-year-old male presented with syncope and worsening difficulty in breathing through the left nostril. Computed tomography demonstrated a tumor in the anterior ethmoid air cells and maxillary sinus, which extended into the frontal lobe. Magnetic resonance imaging similarly demonstrated an aggressive lesion. This mass was difficult to differentiate from more commonly seen lesions at this location such as an esthesioneuroblastoma or nasopharyngeal carcinoma. Direct visualization, biopsy, and subsequent pathologic analysis eventually confirmed the diagnosis of malignant Ewing sarcoma (EWS). Our case explores the radiological findings of EWS originating from the ethmoid sinus, compares EWS with other common carcinomas in the same location, confirms the diagnosis through pathological correlation, and investigates the prognosis and treatment of these lesions. This case highlights the importance of a multidisciplinary approach to diagnose EWS when it occurs in an atypical location. The clinical team relied on input from the radiology, surgery, ENT, neurology, and pathology departments to make an accurate diagnosis and plan treatment for this aggressive tumor. Cureus 2023-08-18 /pmc/articles/PMC10505484/ /pubmed/37724222 http://dx.doi.org/10.7759/cureus.43708 Text en Copyright © 2023, Worthy et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Worthy, Jennifer
Ganguli, Malika P
Kile, Mahlon R
Satei, Alexander M
Mills, Nicholas D
A Rare Case of Sinonasal Ewing Sarcoma With Radiologic-Pathologic Correlation
title A Rare Case of Sinonasal Ewing Sarcoma With Radiologic-Pathologic Correlation
title_full A Rare Case of Sinonasal Ewing Sarcoma With Radiologic-Pathologic Correlation
title_fullStr A Rare Case of Sinonasal Ewing Sarcoma With Radiologic-Pathologic Correlation
title_full_unstemmed A Rare Case of Sinonasal Ewing Sarcoma With Radiologic-Pathologic Correlation
title_short A Rare Case of Sinonasal Ewing Sarcoma With Radiologic-Pathologic Correlation
title_sort rare case of sinonasal ewing sarcoma with radiologic-pathologic correlation
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505484/
https://www.ncbi.nlm.nih.gov/pubmed/37724222
http://dx.doi.org/10.7759/cureus.43708
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