Cargando…
chem16S: community-level chemical metrics for exploring genomic adaptation to environments
SUMMARY: The chem16S package combines taxonomic classifications of 16S rRNA gene sequences with amino acid compositions of prokaryotic reference proteomes to generate community reference proteomes. Taxonomic classifications from the RDP Classifier or data objects created by the phyloseq R package ar...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505500/ https://www.ncbi.nlm.nih.gov/pubmed/37688565 http://dx.doi.org/10.1093/bioinformatics/btad564 |
_version_ | 1785106924494127104 |
---|---|
author | Dick, Jeffrey M Kang, Xun |
author_facet | Dick, Jeffrey M Kang, Xun |
author_sort | Dick, Jeffrey M |
collection | PubMed |
description | SUMMARY: The chem16S package combines taxonomic classifications of 16S rRNA gene sequences with amino acid compositions of prokaryotic reference proteomes to generate community reference proteomes. Taxonomic classifications from the RDP Classifier or data objects created by the phyloseq R package are supported. Users can calculate and visualize a variety of chemical metrics in order to explore the effects of redox, salinity, and other physicochemical variables on the genomic adaptation of protein sequences at the community level. AVAILABILITY AND IMPLEMENTATION: Development of chem16S is hosted at https://github.com/jedick/chem16S. Version 1.0.0 is freely available from the Comprehensive R Archive Network (CRAN) at https://cran.r-project.org/package=chem16S. |
format | Online Article Text |
id | pubmed-10505500 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-105055002023-09-18 chem16S: community-level chemical metrics for exploring genomic adaptation to environments Dick, Jeffrey M Kang, Xun Bioinformatics Applications Note SUMMARY: The chem16S package combines taxonomic classifications of 16S rRNA gene sequences with amino acid compositions of prokaryotic reference proteomes to generate community reference proteomes. Taxonomic classifications from the RDP Classifier or data objects created by the phyloseq R package are supported. Users can calculate and visualize a variety of chemical metrics in order to explore the effects of redox, salinity, and other physicochemical variables on the genomic adaptation of protein sequences at the community level. AVAILABILITY AND IMPLEMENTATION: Development of chem16S is hosted at https://github.com/jedick/chem16S. Version 1.0.0 is freely available from the Comprehensive R Archive Network (CRAN) at https://cran.r-project.org/package=chem16S. Oxford University Press 2023-09-09 /pmc/articles/PMC10505500/ /pubmed/37688565 http://dx.doi.org/10.1093/bioinformatics/btad564 Text en © The Author(s) 2023. Published by Oxford University Press. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Applications Note Dick, Jeffrey M Kang, Xun chem16S: community-level chemical metrics for exploring genomic adaptation to environments |
title |
chem16S: community-level chemical metrics for exploring genomic adaptation to environments |
title_full |
chem16S: community-level chemical metrics for exploring genomic adaptation to environments |
title_fullStr |
chem16S: community-level chemical metrics for exploring genomic adaptation to environments |
title_full_unstemmed |
chem16S: community-level chemical metrics for exploring genomic adaptation to environments |
title_short |
chem16S: community-level chemical metrics for exploring genomic adaptation to environments |
title_sort | chem16s: community-level chemical metrics for exploring genomic adaptation to environments |
topic | Applications Note |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505500/ https://www.ncbi.nlm.nih.gov/pubmed/37688565 http://dx.doi.org/10.1093/bioinformatics/btad564 |
work_keys_str_mv | AT dickjeffreym chem16scommunitylevelchemicalmetricsforexploringgenomicadaptationtoenvironments AT kangxun chem16scommunitylevelchemicalmetricsforexploringgenomicadaptationtoenvironments |