Hypoxia-inducible factor upregulation by roxadustat attenuates drug reward by altering brain iron homoeostasis

Substance use disorder remains a major challenge, with an enduring need to identify and evaluate new, translational targets for effective treatment. Here, we report the upregulation of Hypoxia-inducible factor-1α (HIF-1α) expression by roxadustat (Rox), a drug developed for renal anemia that inhibit...

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Detalles Bibliográficos
Autores principales: Yan, Pengju, Li, Ningning, Ma, Ming, Liu, Zhaoli, Yang, Huicui, Li, Jinnan, Wan, Chunlei, Gao, Shuliu, Li, Shuai, Zheng, Longtai, Waddington, John L., Xu, Lin, Zhen, Xuechu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505610/
https://www.ncbi.nlm.nih.gov/pubmed/37718358
http://dx.doi.org/10.1038/s41392-023-01578-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505610/
https://www.ncbi.nlm.nih.gov/pubmed/37718358
http://dx.doi.org/10.1038/s41392-023-01578-2

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