Testis exposure to unopposed/elevated activin A in utero affects somatic and germ cells and alters steroid levels mimicking phthalate exposure

Correct fetal testis development underpins adult male fertility, and TGFβ superfamily ligands control key aspects of this process. Transcripts encoding one such ligand, activin A, are upregulated in testes after sex determination and remain high until after birth. Testis development requires activin...

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Detalles Bibliográficos
Autores principales: Whiley, Penny A. F., Luu, Michael C. M., O’Donnell, Liza, Handelsman, David J., Loveland, Kate L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505732/
https://www.ncbi.nlm.nih.gov/pubmed/37727456
http://dx.doi.org/10.3389/fendo.2023.1234712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505732/
https://www.ncbi.nlm.nih.gov/pubmed/37727456
http://dx.doi.org/10.3389/fendo.2023.1234712

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