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RNF26 binds perinuclear vimentin filaments to integrate ER and endolysosomal responses to proteotoxic stress
Proteotoxic stress causes profound endoplasmic reticulum (ER) membrane remodeling into a perinuclear quality control compartment (ERQC) for the degradation of misfolded proteins. Subsequent return to homeostasis involves clearance of the ERQC by endolysosomes. However, the factors that control perin...
Autores principales: | Cremer, Tom, Voortman, Lenard M, Bos, Erik, Jongsma, Marlieke LM, ter Haar, Laurens R, Akkermans, Jimmy JLL, Talavera Ormeño, Cami MP, Wijdeven, Ruud HM, de Vries, Jelle, Kim, Robbert Q, Janssen, George MC, van Veelen, Peter A, Koning, Roman I, Neefjes, Jacques, Berlin, Ilana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505911/ https://www.ncbi.nlm.nih.gov/pubmed/37519262 http://dx.doi.org/10.15252/embj.2022111252 |
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