Cargando…

Plant YTHDF proteins are direct effectors of antiviral immunity against an N6 ‐methyladenosine‐containing RNA virus

In virus–host interactions, nucleic acid‐directed first lines of defense that allow viral clearance without compromising growth are of paramount importance. Plants use the RNA interference pathway as a basal antiviral immune system, but additional RNA‐based mechanisms of defense also exist. The infe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Martínez‐Pérez, Mireya, Aparicio, Frederic, Arribas‐Hernández, Laura, Tankmar, Mathias Due, Rennie, Sarah, von Bülow, Sören, Lindorff‐Larsen, Kresten, Brodersen, Peter, Pallas, Vicente
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505913/ https://www.ncbi.nlm.nih.gov/pubmed/37431920 http://dx.doi.org/10.15252/embj.2022113378

Ejemplares similares

Insights into the conservation and diversification of the molecular functions of YTHDF proteins
por: Flores-Téllez, Daniel, et al.
Publicado: (2023)

The YTHDF proteins ECT2 and ECT3 bind largely overlapping target sets and influence target mRNA abundance, not alternative polyadenylation
por: Arribas-Hernández, Laura, et al.
Publicado: (2021)

N6-methyladenosine reader YTHDF family in biological processes: Structures, roles, and mechanisms
por: Chen, Lin, et al.
Publicado: (2023)

Improved predictions of phase behaviour of intrinsically disordered proteins by tuning the interaction range
por: Tesei, Giulio, et al.
Publicado: (2023)

Small-Molecule Ebselen Binds to YTHDF Proteins Interfering with the Recognition of N(6)-Methyladenosine-Modified RNAs
por: Micaelli, Mariachiara, et al.
Publicado: (2022)

Similarity Measures for Protein Ensembles
por: Lindorff-Larsen, Kresten, et al.
Publicado: (2009)

Recent Acquisition of Functional m6A RNA Demethylase Domain in Orchid Ty3/Gypsy Elements
por: Alvarado-Marchena, Luis, et al.
Publicado: (2022)

N(6)‐methyladenosine‐binding protein YTHDF1 suppresses EBV replication and promotes EBV RNA decay
por: Xia, Tian‐Liang, et al.
Publicado: (2021)

FBW7 suppresses ovarian cancer development by targeting the N(6)-methyladenosine binding protein YTHDF2
por: Xu, Fei, et al.
Publicado: (2021)

N6‐methyladenosine reader YTHDF3 regulates melanoma metastasis via its ‘executor'LOXL3
por: Shi, Hao‐ze, et al.
Publicado: (2022)

Mapping transiently formed and sparsely populated conformations on a complex energy landscape
por: Wang, Yong, et al.
Publicado: (2016)

Mapping of Functional Subdomains in the atALKBH9B m(6)A-Demethylase Required for Its Binding to the Viral RNA and to the Coat Protein of Alfalfa Mosaic Virus
por: Alvarado-Marchena, Luis, et al.
Publicado: (2021)

Impact of the Potential m(6)A Modification Sites at the 3′UTR of Alfalfa Mosaic Virus RNA3 in the Viral Infection
por: Alvarado-Marchena, Luis, et al.
Publicado: (2022)

N(6)-Methyladenosine RNA-Binding Protein YTHDF1 in Gastrointestinal Cancers: Function, Molecular Mechanism and Clinical Implication
por: Chen, Danyu, et al.
Publicado: (2022)

Downregulation of N(6)-methyladenosine binding YTHDF2 protein mediated by miR-493-3p suppresses prostate cancer by elevating N(6)-methyladenosine levels
por: Li, Jiangfeng, et al.
Publicado: (2017)

Combining Experiments and Simulations Using the Maximum Entropy Principle
por: Boomsma, Wouter, et al.
Publicado: (2014)

Biomolecular conformational changes and ligand binding: from kinetics to thermodynamics
por: Wang, Yong, et al.
Publicado: (2017)

How well do force fields capture the strength of salt bridges in proteins?
por: Ahmed, Mustapha Carab, et al.
Publicado: (2018)

The N(6)-methyladenosine RNA-binding protein YTHDF1 modulates the translation of TRAF6 to mediate the intestinal immune response
por: Zong, Xin, et al.
Publicado: (2021)

O-GlcNAcylation of YTHDF2 promotes HBV-related hepatocellular carcinoma progression in an N(6)-methyladenosine-dependent manner
por: Yang, Yang, et al.
Publicado: (2023)

Force Field Effects in Simulations of Flexible Peptides with Varying Polyproline II Propensity
por: Jephthah, Stéphanie, et al.
Publicado: (2021)

Slow conformational changes in the rigid and highly stable chymotrypsin inhibitor 2
por: Gavrilov, Yulian, et al.
Publicado: (2023)

N(6)-methyladenosine METTL3 promotes cervical cancer tumorigenesis and Warburg effect through YTHDF1/HK2 modification
por: Wang, Qianqing, et al.
Publicado: (2020)

The N6-Methyladenosine (m6A) Methylation Gene YTHDF1 Reveals a Potential Diagnostic Role for Gastric Cancer
por: Liu, Tong, et al.
Publicado: (2020)

Ythdf is a N6‐methyladenosine reader that modulates Fmr1 target mRNA selection and restricts axonal growth in Drosophila
por: Worpenberg, Lina, et al.
Publicado: (2021)

Bayesian-Maximum-Entropy Reweighting of IDP Ensembles Based on NMR Chemical Shifts
por: Crehuet, Ramon, et al.
Publicado: (2019)

YTHDF2 mediates the mRNA degradation of the tumor suppressors to induce AKT phosphorylation in N6-methyladenosine-dependent way in prostate cancer
por: Li, Jiangfeng, et al.
Publicado: (2020)

METTL3 promotes tumour development by decreasing APC expression mediated by APC mRNA N(6)-methyladenosine-dependent YTHDF binding
por: Wang, Wei, et al.
Publicado: (2021)

Identification and Validation of the N6-Methyladenosine RNA Methylation Regulator YTHDF1 as a Novel Prognostic Marker and Potential Target for Hepatocellular Carcinoma
por: Bian, Saiyan, et al.
Publicado: (2020)

N1-Methyladenosine (m1A) Regulation Associated With the Pathogenesis of Abdominal Aortic Aneurysm Through YTHDF3 Modulating Macrophage Polarization
por: Wu, Yihao, et al.
Publicado: (2022)

Communication Routes in ARID Domains between Distal Residues in Helix 5 and the DNA-Binding Loops
por: Invernizzi, Gaetano, et al.
Publicado: (2014)

ENCORE: Software for Quantitative Ensemble Comparison
por: Tiberti, Matteo, et al.
Publicado: (2015)

Molecular dynamics ensemble refinement of the heterogeneous native state of NCBD using chemical shifts and NOEs
por: Papaleo, Elena, et al.
Publicado: (2018)

Enhancing coevolution-based contact prediction by imposing structural self-consistency of the contacts
por: Kassem, Maher M., et al.
Publicado: (2018)

Multiplexed assays reveal effects of missense variants in MSH2 and cancer predisposition
por: Nielsen, Sofie V., et al.
Publicado: (2021)

Conformational and oligomeric states of SPOP from small-angle X-ray scattering and molecular dynamics simulations
por: Thomasen, F Emil, et al.
Publicado: (2023)

Discovering functionally important sites in proteins
por: Cagiada, Matteo, et al.
Publicado: (2023)

The m(6)A RNA Demethylase ALKBH9B Plays a Critical Role for Vascular Movement of Alfalfa Mosaic Virus in Arabidopsis
por: Martínez-Pérez, Mireya, et al.
Publicado: (2021)

Combining molecular dynamics simulations with small-angle X-ray and neutron scattering data to study multi-domain proteins in solution
por: Larsen, Andreas Haahr, et al.
Publicado: (2020)

Integrating NMR and simulations reveals motions in the UUCG tetraloop
por: Bottaro, Sandro, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_u2fg1ng4sgmrgpfj4kh1kf0a92