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Alanine/EPR dosimetry for mailed intercomparison at ocular proton therapy facilities—preliminary results for three centres for irradaitions at CCB IFJ PAN eyeline

Quality control of therapeutic photon beams in the form of postal dose audits based on passive dosemeters is widely used in photon radiotherapy. On the other hand, no standardised dosimetry audit programme for proton centres has been established in Europe so far. We evaluated alanine/EPR dosimetry s...

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Autores principales: Michalec, Barbara, De Angelis, Cinzia, Foltyńska, Gabriela, Horwacik, Tomasz, Reniers, Brigitte, Wochnik, Agnieszka, Kopeć, Renata, Swakoń, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505937/
https://www.ncbi.nlm.nih.gov/pubmed/37721070
http://dx.doi.org/10.1093/rpd/ncad127
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author Michalec, Barbara
De Angelis, Cinzia
Foltyńska, Gabriela
Horwacik, Tomasz
Reniers, Brigitte
Wochnik, Agnieszka
Kopeć, Renata
Swakoń, Jan
author_facet Michalec, Barbara
De Angelis, Cinzia
Foltyńska, Gabriela
Horwacik, Tomasz
Reniers, Brigitte
Wochnik, Agnieszka
Kopeć, Renata
Swakoń, Jan
author_sort Michalec, Barbara
collection PubMed
description Quality control of therapeutic photon beams in the form of postal dose audits based on passive dosemeters is widely used in photon radiotherapy. On the other hand, no standardised dosimetry audit programme for proton centres has been established in Europe so far. We evaluated alanine/EPR dosimetry systems developed at the Istituto Superiore di Sanità (Italy), the Hasselt Universiteit (Belgium) and the Henryk Niewodniczanski Institute of Nuclear Physics Polish Academy of Sciences (Poland) for their applicability as a potential tool for routine mailed dose audits of passively scattered therapeutic proton beams. The evaluation was carried out in the form of an intercomparison. Dosemeters were irradiated in the 70 MeV proton beam at ocular proton therapy facility in the Cyclotron Centre Bronowice at the Henryk Niewodniczanski Institute of Nuclear Physics Polish Academy of Sciences in Krakow. A very good agreement was found between the dose measured by three laboratories and the delivered dose determined with an ionisation chamber. This, together with the inherent properties of alanine, such as non-destructive readout, tissue equivalence, weak energy dependence, dose rate independence and insignificant fading, makes alanine a good candidate for a dosemeter used in postal auditing in proton ocular radiotherapy.
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spelling pubmed-105059372023-09-19 Alanine/EPR dosimetry for mailed intercomparison at ocular proton therapy facilities—preliminary results for three centres for irradaitions at CCB IFJ PAN eyeline Michalec, Barbara De Angelis, Cinzia Foltyńska, Gabriela Horwacik, Tomasz Reniers, Brigitte Wochnik, Agnieszka Kopeć, Renata Swakoń, Jan Radiat Prot Dosimetry Paper Quality control of therapeutic photon beams in the form of postal dose audits based on passive dosemeters is widely used in photon radiotherapy. On the other hand, no standardised dosimetry audit programme for proton centres has been established in Europe so far. We evaluated alanine/EPR dosimetry systems developed at the Istituto Superiore di Sanità (Italy), the Hasselt Universiteit (Belgium) and the Henryk Niewodniczanski Institute of Nuclear Physics Polish Academy of Sciences (Poland) for their applicability as a potential tool for routine mailed dose audits of passively scattered therapeutic proton beams. The evaluation was carried out in the form of an intercomparison. Dosemeters were irradiated in the 70 MeV proton beam at ocular proton therapy facility in the Cyclotron Centre Bronowice at the Henryk Niewodniczanski Institute of Nuclear Physics Polish Academy of Sciences in Krakow. A very good agreement was found between the dose measured by three laboratories and the delivered dose determined with an ionisation chamber. This, together with the inherent properties of alanine, such as non-destructive readout, tissue equivalence, weak energy dependence, dose rate independence and insignificant fading, makes alanine a good candidate for a dosemeter used in postal auditing in proton ocular radiotherapy. Oxford University Press 2023-09-18 /pmc/articles/PMC10505937/ /pubmed/37721070 http://dx.doi.org/10.1093/rpd/ncad127 Text en © The Author(s) 2023. Published by Oxford University Press. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Paper
Michalec, Barbara
De Angelis, Cinzia
Foltyńska, Gabriela
Horwacik, Tomasz
Reniers, Brigitte
Wochnik, Agnieszka
Kopeć, Renata
Swakoń, Jan
Alanine/EPR dosimetry for mailed intercomparison at ocular proton therapy facilities—preliminary results for three centres for irradaitions at CCB IFJ PAN eyeline
title Alanine/EPR dosimetry for mailed intercomparison at ocular proton therapy facilities—preliminary results for three centres for irradaitions at CCB IFJ PAN eyeline
title_full Alanine/EPR dosimetry for mailed intercomparison at ocular proton therapy facilities—preliminary results for three centres for irradaitions at CCB IFJ PAN eyeline
title_fullStr Alanine/EPR dosimetry for mailed intercomparison at ocular proton therapy facilities—preliminary results for three centres for irradaitions at CCB IFJ PAN eyeline
title_full_unstemmed Alanine/EPR dosimetry for mailed intercomparison at ocular proton therapy facilities—preliminary results for three centres for irradaitions at CCB IFJ PAN eyeline
title_short Alanine/EPR dosimetry for mailed intercomparison at ocular proton therapy facilities—preliminary results for three centres for irradaitions at CCB IFJ PAN eyeline
title_sort alanine/epr dosimetry for mailed intercomparison at ocular proton therapy facilities—preliminary results for three centres for irradaitions at ccb ifj pan eyeline
topic Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505937/
https://www.ncbi.nlm.nih.gov/pubmed/37721070
http://dx.doi.org/10.1093/rpd/ncad127
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