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Successful treatment of a case of COVID-19 pneumonia following kidney transplantation using paxlovid and tocilizumab

BACKGROUND: Since its initial detection in 2019, coronavirus disease 2019 (COVID-19) pneumonia has rapidly spread throughout the world in a global pandemic. However, reports of COVID-19 pneumonia among patients following kidney transplantation have been limited and no uniform treatment guidelines fo...

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Autores principales: Chen, Qian, Niu, Yu-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506020/
https://www.ncbi.nlm.nih.gov/pubmed/37727489
http://dx.doi.org/10.12998/wjcc.v11.i25.6012
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author Chen, Qian
Niu, Yu-Lin
author_facet Chen, Qian
Niu, Yu-Lin
author_sort Chen, Qian
collection PubMed
description BACKGROUND: Since its initial detection in 2019, coronavirus disease 2019 (COVID-19) pneumonia has rapidly spread throughout the world in a global pandemic. However, reports of COVID-19 pneumonia among patients following kidney transplantation have been limited and no uniform treatment guidelines for these patients have yet to be established. CASE SUMMARY: Here, we report the case of a 39-year-old patient recovering from kidney transplantation who contracted perioperative COVID-19 pneumonia that was successfully controlled with oral paxlovid and a single intravenous drip infusion of tocilizumab following the discontinuation of immunosuppressive drugs. CONCLUSION: Given the rapid spread of severe acute respiratory syndrome coronavirus 2 infections, clinicians should be aware of the potential for more cases of COVID-19 among patients following kidney transplantation and be familiar with appropriate treatment options and likely clinical outcomes.
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spelling pubmed-105060202023-09-19 Successful treatment of a case of COVID-19 pneumonia following kidney transplantation using paxlovid and tocilizumab Chen, Qian Niu, Yu-Lin World J Clin Cases Case Report BACKGROUND: Since its initial detection in 2019, coronavirus disease 2019 (COVID-19) pneumonia has rapidly spread throughout the world in a global pandemic. However, reports of COVID-19 pneumonia among patients following kidney transplantation have been limited and no uniform treatment guidelines for these patients have yet to be established. CASE SUMMARY: Here, we report the case of a 39-year-old patient recovering from kidney transplantation who contracted perioperative COVID-19 pneumonia that was successfully controlled with oral paxlovid and a single intravenous drip infusion of tocilizumab following the discontinuation of immunosuppressive drugs. CONCLUSION: Given the rapid spread of severe acute respiratory syndrome coronavirus 2 infections, clinicians should be aware of the potential for more cases of COVID-19 among patients following kidney transplantation and be familiar with appropriate treatment options and likely clinical outcomes. Baishideng Publishing Group Inc 2023-09-06 2023-09-06 /pmc/articles/PMC10506020/ /pubmed/37727489 http://dx.doi.org/10.12998/wjcc.v11.i25.6012 Text en ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Case Report
Chen, Qian
Niu, Yu-Lin
Successful treatment of a case of COVID-19 pneumonia following kidney transplantation using paxlovid and tocilizumab
title Successful treatment of a case of COVID-19 pneumonia following kidney transplantation using paxlovid and tocilizumab
title_full Successful treatment of a case of COVID-19 pneumonia following kidney transplantation using paxlovid and tocilizumab
title_fullStr Successful treatment of a case of COVID-19 pneumonia following kidney transplantation using paxlovid and tocilizumab
title_full_unstemmed Successful treatment of a case of COVID-19 pneumonia following kidney transplantation using paxlovid and tocilizumab
title_short Successful treatment of a case of COVID-19 pneumonia following kidney transplantation using paxlovid and tocilizumab
title_sort successful treatment of a case of covid-19 pneumonia following kidney transplantation using paxlovid and tocilizumab
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506020/
https://www.ncbi.nlm.nih.gov/pubmed/37727489
http://dx.doi.org/10.12998/wjcc.v11.i25.6012
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