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Tanshinone IIA protects motor neuron-like NSC-34 cells against lipopolysaccharide-induced cell injury by the regulation of the lncRNA TCTN2/miR-125a-5p/DUSP1 axis

BACKGROUND: Tanshinone IIA (TSIIA) exerts a protective role in spinal cord injury (SCI). However, the mechanism of TSIIA activity in SCI remains to be elucidated. METHODS: Cell viability and apoptosis were gauged by CCK-8 assay and flow cytometry, respectively. The expression levels of lncRNA TCTN2,...

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Detalles Bibliográficos
Autores principales: Yan, Qiwen, Xun, Yajing, Lei, Debao, Zhai, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506057/
https://www.ncbi.nlm.nih.gov/pubmed/37727797
http://dx.doi.org/10.1016/j.reth.2023.03.007

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