A case of disseminated coccidioidomycosis and immune reconstitution inflammatory syndrome (IRIS) in a patient with HIV/AIDS

Coccidioidomycosis is a fungal infection endemic to the southwestern United States and Central/South America, and its range is expanding with the warming climate. People with HIV/AIDS are at increased risk of developing disseminated infection, and furthermore are at risk for developing immune recons...

Descripción completa

Detalles Bibliográficos
Autores principales: Kaplan, Samantha R., Rajagopal, Amutha, Cachay, Edward R., Deiss, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506086/
https://www.ncbi.nlm.nih.gov/pubmed/37727860
http://dx.doi.org/10.1016/j.idcr.2023.e01896
_version_ 1785107046801080320
author Kaplan, Samantha R.
Rajagopal, Amutha
Cachay, Edward R.
Deiss, Robert
author_facet Kaplan, Samantha R.
Rajagopal, Amutha
Cachay, Edward R.
Deiss, Robert
author_sort Kaplan, Samantha R.
collection PubMed
description Coccidioidomycosis is a fungal infection endemic to the southwestern United States and Central/South America, and its range is expanding with the warming climate. People with HIV/AIDS are at increased risk of developing disseminated infection, and furthermore are at risk for developing immune reconstitution inflammatory syndrome (IRIS) if they are initiating or re-initiating anti-retroviral therapy (ART). There have been few cases of coccidioidomycosis-related IRIS reported in the literature, and there is no clear guidance on treatment. We present a case of paradoxical IRIS in a patient with AIDS who clinically improved after initiating corticosteroids.
format Online
Article
Text
id pubmed-10506086
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-105060862023-09-19 A case of disseminated coccidioidomycosis and immune reconstitution inflammatory syndrome (IRIS) in a patient with HIV/AIDS Kaplan, Samantha R. Rajagopal, Amutha Cachay, Edward R. Deiss, Robert IDCases Case Report Coccidioidomycosis is a fungal infection endemic to the southwestern United States and Central/South America, and its range is expanding with the warming climate. People with HIV/AIDS are at increased risk of developing disseminated infection, and furthermore are at risk for developing immune reconstitution inflammatory syndrome (IRIS) if they are initiating or re-initiating anti-retroviral therapy (ART). There have been few cases of coccidioidomycosis-related IRIS reported in the literature, and there is no clear guidance on treatment. We present a case of paradoxical IRIS in a patient with AIDS who clinically improved after initiating corticosteroids. Elsevier 2023-09-09 /pmc/articles/PMC10506086/ /pubmed/37727860 http://dx.doi.org/10.1016/j.idcr.2023.e01896 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kaplan, Samantha R.
Rajagopal, Amutha
Cachay, Edward R.
Deiss, Robert
A case of disseminated coccidioidomycosis and immune reconstitution inflammatory syndrome (IRIS) in a patient with HIV/AIDS
title A case of disseminated coccidioidomycosis and immune reconstitution inflammatory syndrome (IRIS) in a patient with HIV/AIDS
title_full A case of disseminated coccidioidomycosis and immune reconstitution inflammatory syndrome (IRIS) in a patient with HIV/AIDS
title_fullStr A case of disseminated coccidioidomycosis and immune reconstitution inflammatory syndrome (IRIS) in a patient with HIV/AIDS
title_full_unstemmed A case of disseminated coccidioidomycosis and immune reconstitution inflammatory syndrome (IRIS) in a patient with HIV/AIDS
title_short A case of disseminated coccidioidomycosis and immune reconstitution inflammatory syndrome (IRIS) in a patient with HIV/AIDS
title_sort case of disseminated coccidioidomycosis and immune reconstitution inflammatory syndrome (iris) in a patient with hiv/aids
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506086/
https://www.ncbi.nlm.nih.gov/pubmed/37727860
http://dx.doi.org/10.1016/j.idcr.2023.e01896
work_keys_str_mv AT kaplansamanthar acaseofdisseminatedcoccidioidomycosisandimmunereconstitutioninflammatorysyndromeirisinapatientwithhivaids
AT rajagopalamutha acaseofdisseminatedcoccidioidomycosisandimmunereconstitutioninflammatorysyndromeirisinapatientwithhivaids
AT cachayedwardr acaseofdisseminatedcoccidioidomycosisandimmunereconstitutioninflammatorysyndromeirisinapatientwithhivaids
AT deissrobert acaseofdisseminatedcoccidioidomycosisandimmunereconstitutioninflammatorysyndromeirisinapatientwithhivaids
AT kaplansamanthar caseofdisseminatedcoccidioidomycosisandimmunereconstitutioninflammatorysyndromeirisinapatientwithhivaids
AT rajagopalamutha caseofdisseminatedcoccidioidomycosisandimmunereconstitutioninflammatorysyndromeirisinapatientwithhivaids
AT cachayedwardr caseofdisseminatedcoccidioidomycosisandimmunereconstitutioninflammatorysyndromeirisinapatientwithhivaids
AT deissrobert caseofdisseminatedcoccidioidomycosisandimmunereconstitutioninflammatorysyndromeirisinapatientwithhivaids

Ejemplares similares