Cargando…

Beta-subunit-eliminated eHAP expression (BeHAPe) cells reveal subunit regulation of the cardiac voltage-gated sodium channel

Voltage-gated sodium (Na(V)) channels drive the upstroke of the action potential and are comprised of a pore-forming α-subunit and regulatory β-subunits. The β-subunits modulate the gating, trafficking, and pharmacology of the α-subunit. These functions are routinely assessed by ectopic expression i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Minard, Annabel Y., Clark, Colin J., Ahern, Christopher A., Piper, Robert C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Methods and Resources
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506104/ https://www.ncbi.nlm.nih.gov/pubmed/37544648 http://dx.doi.org/10.1016/j.jbc.2023.105132

Ejemplares similares

Structure-based assessment of disease-related mutations in human voltage-gated sodium channels
por: Huang, Weiyun, et al.
Publicado: (2017)

Trafficking and Function of the Voltage-Gated Sodium Channel β2 Subunit
por: Cortada, Eric, et al.
Publicado: (2019)

The Voltage-Gated Sodium Channel Beta4 Subunit Maintains Epithelial Phenotype in Mammary Cells
por: Doray, Adélaïde, et al.
Publicado: (2021)

Computational Investigation of Voltage-Gated Sodium Channel β3 Subunit Dynamics
por: Glass, William G., et al.
Publicado: (2020)

Identification of BACE1 cleavage sites in human voltage-gated sodium channel beta 2 subunit
por: Gersbacher, Manuel T, et al.
Publicado: (2010)

On the multiple roles of the voltage gated sodium channel β1 subunit in genetic diseases
por: Baroni, Debora, et al.
Publicado: (2015)

The Mycoplasma pneumoniae HapE alters the cytokine profile and growth of human bronchial epithelial cells
por: Li, Shaoli, et al.
Publicado: (2019)

Contribution of voltage-gated sodium channel β-subunits to cervical cancer cells metastatic behavior
por: Sanchez-Sandoval, Ana Laura, et al.
Publicado: (2019)

Structural basis of HapE(P88L)-linked antifungal triazole resistance in Aspergillus fumigatus
por: Hortschansky, Peter, et al.
Publicado: (2020)

Strong cooperativity between subunits in voltage-gated proton channels
por: Gonzalez, Carlos, et al.
Publicado: (2009)

β subunits of voltage-gated calcium channels in cardiovascular diseases
por: Loh, Kelvin Wei Zhern, et al.
Publicado: (2023)

Molecular cloning and analysis of zebrafish voltage-gated sodium channel beta subunit genes: implications for the evolution of electrical signaling in vertebrates
por: Chopra, Sameer S, et al.
Publicado: (2007)

pHAPE: a plasmid for production of DNA size marker ladders for gel electrophoresis
por: Allen, Angel G, et al.
Publicado: (2023)

Reporters to mark and eliminate basal or luminal epithelial cells in culture and in vivo
por: Sonzogni, Olmo, et al.
Publicado: (2018)

Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation
por: Hawley, Simon A., et al.
Publicado: (2010)

Voltage-Gated Sodium Channel β1/β1B Subunits Regulate Cardiac Physiology and Pathophysiology
por: Edokobi, Nnamdi, et al.
Publicado: (2018)

Functional modulation of the human voltage-gated sodium channel Na(V)1.8 by auxiliary β subunits
por: Nevin, S. T., et al.
Publicado: (2020)

Regulation of Voltage-Activated K(+) Channel Gating by Transmembrane β Subunits
por: Sun, Xiaohui, et al.
Publicado: (2012)

The Role of Auxiliary Subunits for the Functional Diversity of Voltage-Gated Calcium Channels
por: Campiglio, Marta, et al.
Publicado: (2015)

Voltage‐gated calcium channels and their auxiliary subunits: physiology and pathophysiology and pharmacology
por: Dolphin, Annette C.
Publicado: (2016)

The hitchhiker’s guide to the voltage-gated sodium channel galaxy
por: Ahern, Christopher A., et al.
Publicado: (2016)

VGIchan: Prediction and Classification of Voltage-Gated Ion Channels
por: Saha, Sudipto, et al.
Publicado: (2006)

Discovery of a hapE Mutation That Causes Azole Resistance in Aspergillus fumigatus through Whole Genome Sequencing and Sexual Crossing
por: Camps, Simone M. T., et al.
Publicado: (2012)

Clinical and experimental phenotype of azole-resistant Aspergillus fumigatus with a HapE splice site mutation: a case report
por: Ito, Yuya, et al.
Publicado: (2021)

Regulatory Role of Voltage-Gated Na(+) Channel β Subunits in Sensory Neurons
por: Chahine, Mohamed, et al.
Publicado: (2011)

The β(2)-Subunit of Voltage-Gated Calcium Channels Regulates Cardiomyocyte Hypertrophy
por: Pickel, Simone, et al.
Publicado: (2021)

HapZipper: sharing HapMap populations just got easier
por: Chanda, Pritam, et al.
Publicado: (2012)

Gating by Cyclic Gmp and Voltage in the α Subunit of the Cyclic Gmp–Gated Channel from Rod Photoreceptors
por: Benndorf, Klaus, et al.
Publicado: (1999)

Intron Retention in mRNA Encoding Ancillary Subunit of Insect Voltage-Gated Sodium Channel Modulates Channel Expression, Gating Regulation and Drug Sensitivity
por: Bourdin, Céline M., et al.
Publicado: (2013)

Database of glutamate-gated chloride (GluCl) subunits across 125 nematode species: patterns of gene accretion and sequence diversification
por: O’Halloran, Damien M
Publicado: (2021)

Correction to: Clinical and experimental phenotype of azole-resistant Aspergillus fumigatus with a HapE splice site mutation: a case report
por: Ito, Yuya, et al.
Publicado: (2021)

hapE and hmg1 Mutations Are Drivers of cyp51A-Independent Pan-Triazole Resistance in an Aspergillus fumigatus Clinical Isolate
por: Souza, Ana C. O., et al.
Publicado: (2023)

A hierarchical model for assembly of eukaryotic 60S ribosomal subunit domains
por: Gamalinda, Michael, et al.
Publicado: (2014)

Nanoenviroments of the β-Subunit of L-Type Voltage-Gated Calcium Channels in Adult Cardiomyocytes
por: Cruz-Garcia, Yiliam, et al.
Publicado: (2022)

Dynamic phospholipid interaction of β2e subunit regulates the gating of voltage-gated Ca(2+) channels
por: Kim, Dong-Il, et al.
Publicado: (2015)

Cellular abundance of sodium phosphate cotransporter SLC20A1/PiT1 and phosphate uptake are controlled post-transcriptionally by ESCRT
por: Zechner, Christoph, et al.
Publicado: (2022)

Neutralization of Gating Charges in Domain II of the Sodium Channel α Subunit Enhances Voltage-Sensor Trapping by a β-Scorpion Toxin
por: Cestèle, Sandrine, et al.
Publicado: (2001)

Structure-based site-directed photo-crosslinking analyses of multimeric cell-adhesive interactions of voltage-gated sodium channel β subunits
por: Shimizu, Hideaki, et al.
Publicado: (2016)

RNA Polymerase III Subunit POLR3G Regulates Specific Subsets of PolyA(+) and SmallRNA Transcriptomes and Splicing in Human Pluripotent Stem Cells
por: Lund, Riikka J., et al.
Publicado: (2017)

The HOOK region of voltage-gated Ca(2+) channel β subunits senses and transmits PIP(2) signals to the gate
por: Park, Cheon-Gyu, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_f8q6loqto3gli20jkr843va1ov