Cargando…
GDF15 affects venous thrombosis by promoting EndMT through smad2/p-smad2 pathway
BACKGROUND: Endothelial-to-mesenchymal transition (EndMT) is a pathophysiological change in the vascular endothelium commonly seen in the cardiovascular system. Elevated serum Growth differiention factor 15 (GDF15) has been reported in VTE patients, but the relationship and mechanism between GDF15,...
Autores principales: | Li, Yeping, Zhu, Huiqi, Xin, Wanghao, Wang, Jiaoyan, Yan, Chao, Ying, Kejing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506185/ https://www.ncbi.nlm.nih.gov/pubmed/37723495 http://dx.doi.org/10.1186/s12959-023-00547-7 |
Ejemplares similares
-
To be EndMT or not to be, that is the question in pulmonary hypertension
por: Xiong, Jianhua
Publicado: (2015) -
KRAS mutation-induced EndMT of brain arteriovenous malformation is mediated through the TGF-β/BMP-SMAD4 pathway
por: Xu, Hongyuan, et al.
Publicado: (2022) -
Foxm1 is a critical driver of TGF‐β‐induced EndMT in endothelial cells through Smad2/3 and binds to the Snail promoter
por: Song, Shuai, et al.
Publicado: (2018) -
miR-494 induces EndMT and promotes the development of HCC (Hepatocellular Carcinoma) by targeting SIRT3/TGF-β/SMAD signaling pathway
por: Zhang, Jinqian, et al.
Publicado: (2019) -
Dapagliflozin alleviates cardiac fibrosis through suppressing EndMT and fibroblast activation via AMPKα/TGF‐β/Smad signalling in type 2 diabetic rats
por: Tian, Jingjing, et al.
Publicado: (2021)