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Regulation of phosphoglycerate kinase 1 and its critical role in cancer

Cells that undergo normal differentiation mainly rely on mitochondrial oxidative phosphorylation to provide energy, but most tumour cells rely on aerobic glycolysis. This phenomenon is called the "Warburg effect". Phosphoglycerate kinase 1 (PGK1) is a key enzyme in aerobic glycolysis. PGK1...

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Detalles Bibliográficos
Autores principales: Zhang, Kexin, Sun, Lixue, Kang, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506215/
https://www.ncbi.nlm.nih.gov/pubmed/37723547
http://dx.doi.org/10.1186/s12964-023-01256-4