Cargando…

The novel oncogenic factor TET3 combines with AHR to promote thyroid cancer lymphangiogenesis via the HIF-1α/VEGF signaling pathway

BACKGROUND: Lymphangiogenesis has been reported to play crucial roles in the metastasis of thyroid cancer (THCA), but despite the significant research on lymphangiogenesis in THCA, the precise regulatory mechanism remains unclear. METHODS: Public databases including the Cancer Genome Atlas (TCGA), T...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Liyun, Zhao, Runyu, Qiao, Peipei, Cui, Jiaxin, Chen, Xiaoping, Fan, Jinping, Hu, An, Huang, Shuixian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506260/ https://www.ncbi.nlm.nih.gov/pubmed/37718440 http://dx.doi.org/10.1186/s12935-023-03021-6

Ejemplares similares

C/EBP-δ regulates VEGF-C autocrine signaling in lymphangiogenesis and metastasis of lung cancer through HIF-1α
por: Min, Yongfen, et al.
Publicado: (2011)

CAFs-derived rho-associated kinase1 mediated EMT to promote laryngeal squamous cell carcinoma metastasis
por: Yang, Liyun, et al.
Publicado: (2023)

Crosstalk between ROCK1 and PYROXD1 regulates CAFs activation and promotes laryngeal squamous cell carcinoma metastasis
por: Yang, Liyun, et al.
Publicado: (2022)

BANCR positively regulates the HIF-1α/VEGF-C/VEGFR-3 pathway in a hypoxic microenvironment to promote lymphangiogenesis in pancreatic cancer cells
por: Hao, Shaolong, et al.
Publicado: (2022)

AhR and HIF-1α Signaling Pathways in Benign Meningioma under Hypoxia
por: Perepechaeva, Maria L., et al.
Publicado: (2023)

Enhancement of Lymphangiogenesis In Vitro via the Regulations of HIF-1α Expression and Nuclear Translocation by Deoxyshikonin
por: Prangsaengtong, Orawin, et al.
Publicado: (2013)

Everolimus downregulates STAT3/HIF-1α/VEGF pathway to inhibit angiogenesis and lymphangiogenesis in TP53 mutant head and neck squamous cell carcinoma (HNSCC)
por: Alam, Md Maksudul, et al.
Publicado: (2023)

Rho-associated kinase1 promotes laryngeal squamous cell carcinoma tumorigenesis and progression via the FAK signaling pathway
por: Yang, Liyun, et al.
Publicado: (2022)

The DEK oncogene activates VEGF expression and promotes tumor angiogenesis and growth in HIF-1α-dependent and -independent manners
por: Zhang, Yanan, et al.
Publicado: (2016)

IL-1RA inhibits esophageal carcinogenesis and lymphangiogenesis via downregulating VEGF-C and MMP9
por: Shen, Zhimin, et al.
Publicado: (2023)

Hypoxia switches TET1 from being tumor-suppressive to oncogenic
por: Yang, Qi, et al.
Publicado: (2023)

Association of Age with the Expression of Hypoxia-Inducible Factors HIF-1α, HIF-2α, HIF-3α and VEGF in Lung and Heart of Tibetan Sheep
por: He, Yanyu, et al.
Publicado: (2019)

Interaction between AhR and HIF-1 signaling pathways mediated by ARNT/HIF-1β
por: Zhang, Mengdi, et al.
Publicado: (2022)

Sulfatase 2 facilitates lymphangiogenesis in breast cancer by regulating VEGF-D
por: Zhu, Chenfang, et al.
Publicado: (2016)

Foxp3 is correlated with VEGF-C expression and lymphangiogenesis in cervical cancer
por: Tang, Jiabu, et al.
Publicado: (2017)

Roles of the TGF-β–VEGF-C Pathway in Fibrosis-Related Lymphangiogenesis
por: Kinashi, Hiroshi, et al.
Publicado: (2018)

Characterizing Lymphangiogenesis and Concurrent Inflammation in Adipose Tissue in Response to VEGF-D
por: Chakraborty, Adri, et al.
Publicado: (2020)

VEGF and VEGF type C play an important role in angiogenesis and lymphangiogenesis in human malignant mesothelioma tumours
por: Ohta, Y, et al.
Publicado: (1999)

Lymphangiogenesis in Gastric Cancer regulated through Akt/mTOR-VEGF-C/VEGF-D axis
por: Chen, Hongxia, et al.
Publicado: (2015)

Expression of VEGF, its receptors, and HIF-1α in Dupuytren’s disease
por: Holzer, Lukas A, et al.
Publicado: (2013)

Multi-level interaction between HIF and AHR transcriptional pathways in kidney carcinoma
por: Lafleur, Véronique N, et al.
Publicado: (2023)

VEGF-A expression by HSV-1–infected cells drives corneal lymphangiogenesis
por: Wuest, Todd R., et al.
Publicado: (2010)

Lymphangiogenesis and Its Correlation with the VEGF Expression and the Sentinel Lymph Node in Cutaneous Melanomas
por: Buzrla, Petr, et al.
Publicado: (2014)

CD146 is required for VEGF-C-induced lymphatic sprouting during lymphangiogenesis
por: Yan, Huiwen, et al.
Publicado: (2017)

Promotion of Lymphangiogenesis by Targeted Delivery of VEGF-C Improves Diabetic Wound Healing
por: Brunner, Lorenz M., et al.
Publicado: (2023)

Aloe-emodin suppresses hypoxia-induced retinal angiogenesis via inhibition of HIF-1α/VEGF pathway
por: Wu, Jianming, et al.
Publicado: (2016)

HIF1α inhibition facilitates Leflunomide-AHR-CRP signaling to attenuate bone erosion in CRP-aberrant rheumatoid arthritis
por: Liang, Chao, et al.
Publicado: (2019)

Isopsoralen Enhanced Osteogenesis by Targeting AhR/ERα
por: Ge, Luna, et al.
Publicado: (2018)

Rapamycin suppresses angiogenesis and lymphangiogenesis in melanoma by downregulating VEGF-A/VEGFR-2 and VEGF-C/VEGFR-3 expression
por: Wang, Min, et al.
Publicado: (2019)

Retinal VEGF-A Overexpression Is Not Sufficient to Induce Lymphangiogenesis Regardless of VEGF-C Upregulation and Lyve1(+) Macrophage Infiltration
por: Wada, Iori, et al.
Publicado: (2021)

Copper activates HIF-1α/GPER/VEGF signalling in cancer cells
por: Rigiracciolo, Damiano Cosimo, et al.
Publicado: (2015)

Effect of Moxibustion on HIF-1α and VEGF Levels in Patients with Rheumatoid Arthritis
por: Gong, Yuanyuan, et al.
Publicado: (2019)

HIF1α/VEGF Feedback Loop Contributes to 5-Fluorouracil Resistance
por: Shi, Bin, et al.
Publicado: (2022)

Tet1 facilitates hypoxia tolerance by stabilizing the HIF-α proteins independent of its methylcytosine dioxygenase activity
por: Wang, Jing, et al.
Publicado: (2017)

HIF1α/TET1 Pathway Mediates Hypoxia-Induced Adipocytokine Promoter Hypomethylation in Human Adipocytes
por: Ali, Mohamed M., et al.
Publicado: (2020)

Changes in the Anatomic and Microscopic Structure and the Expression of HIF-1α and VEGF of the Yak Heart with Aging and Hypoxia
por: He, Yanyu, et al.
Publicado: (2016)

Curcumin induces apoptosis in human hepatocellular carcinoma cells by decreasing the expression of STAT3/VEGF/HIF-1α signaling
por: Wang, Xiaoping, et al.
Publicado: (2023)

Coexpression of VEGF-C and COX-2 and its association with lymphangiogenesis in human breast cancer
por: Zhang, Xiao-Hua, et al.
Publicado: (2008)

VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis
por: Hirakawa, Satoshi, et al.
Publicado: (2005)

Expressions of COX-2 and VEGF-C in gastric cancer: correlations with lymphangiogenesis and prognostic implications
por: Gou, Hong-Feng, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_0rcu4clpnjoo6kui233jtndsu4