BK viraemia as a cause of anaemia in after ABO-incompatible liver transplant: a case report

BACKGROUND: While anaemia following liver transplant is common, anaemia in the context of BK viraemia is not a commonly recognised phenomenon. CASE PRESENTATION: We present the case of 59-year old gentleman with severe anaemia in the context of BK viraemia and nephropathy following ABO incompatible...

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Autores principales: McMullen, Lucy, Khoo, Liane, Anderson, Lyndal, Strasser, Simone, Gracey, David M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506278/
https://www.ncbi.nlm.nih.gov/pubmed/37723433
http://dx.doi.org/10.1186/s12879-023-08601-5
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author McMullen, Lucy
Khoo, Liane
Anderson, Lyndal
Strasser, Simone
Gracey, David M
author_facet McMullen, Lucy
Khoo, Liane
Anderson, Lyndal
Strasser, Simone
Gracey, David M
author_sort McMullen, Lucy
collection PubMed
description BACKGROUND: While anaemia following liver transplant is common, anaemia in the context of BK viraemia is not a commonly recognised phenomenon. CASE PRESENTATION: We present the case of 59-year old gentleman with severe anaemia in the context of BK viraemia and nephropathy following ABO incompatible liver transplant. Severity of anaemia appeared to correlate with high titres of BK virus in the serum. Bone marrow biopsy revealed hypocellular marrow with normal cytogenetics. Anaemia improved with treatment with cidofovir, intravenous immunoglobulin, reduction in immunosuppression and erythropoietin stimulating agent. CONCLUSION: To our knowledge, this is the first case of anaemia post liver transplant contributed to by BK viraemia.
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spelling pubmed-105062782023-09-19 BK viraemia as a cause of anaemia in after ABO-incompatible liver transplant: a case report McMullen, Lucy Khoo, Liane Anderson, Lyndal Strasser, Simone Gracey, David M BMC Infect Dis Case Report BACKGROUND: While anaemia following liver transplant is common, anaemia in the context of BK viraemia is not a commonly recognised phenomenon. CASE PRESENTATION: We present the case of 59-year old gentleman with severe anaemia in the context of BK viraemia and nephropathy following ABO incompatible liver transplant. Severity of anaemia appeared to correlate with high titres of BK virus in the serum. Bone marrow biopsy revealed hypocellular marrow with normal cytogenetics. Anaemia improved with treatment with cidofovir, intravenous immunoglobulin, reduction in immunosuppression and erythropoietin stimulating agent. CONCLUSION: To our knowledge, this is the first case of anaemia post liver transplant contributed to by BK viraemia. BioMed Central 2023-09-18 /pmc/articles/PMC10506278/ /pubmed/37723433 http://dx.doi.org/10.1186/s12879-023-08601-5 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
McMullen, Lucy
Khoo, Liane
Anderson, Lyndal
Strasser, Simone
Gracey, David M
BK viraemia as a cause of anaemia in after ABO-incompatible liver transplant: a case report
title BK viraemia as a cause of anaemia in after ABO-incompatible liver transplant: a case report
title_full BK viraemia as a cause of anaemia in after ABO-incompatible liver transplant: a case report
title_fullStr BK viraemia as a cause of anaemia in after ABO-incompatible liver transplant: a case report
title_full_unstemmed BK viraemia as a cause of anaemia in after ABO-incompatible liver transplant: a case report
title_short BK viraemia as a cause of anaemia in after ABO-incompatible liver transplant: a case report
title_sort bk viraemia as a cause of anaemia in after abo-incompatible liver transplant: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506278/
https://www.ncbi.nlm.nih.gov/pubmed/37723433
http://dx.doi.org/10.1186/s12879-023-08601-5
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