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Human astrovirus capsid protein releases a membrane lytic peptide upon trypsin maturation

The human astrovirus (HAstV) is a non-enveloped, single-stranded RNA virus that is a common cause of gastroenteritis. Most non-enveloped viruses use membrane disruption to deliver the viral genome into a host cell after virus uptake. The virus–host factors that allow for HAstV cell entry are current...

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Detalles Bibliográficos
Autores principales: Ykema, Matthew, Ye, Kai, Xun, Meng, Harper, Justin, Betancourt-Solis, Miguel A., Arias, Carlos F., McNew, James A., Tao, Yizhi Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506485/
https://www.ncbi.nlm.nih.gov/pubmed/37504573
http://dx.doi.org/10.1128/jvi.00802-23