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Análisis comparativo de la deformación miocárdica en pacientes recuperados de infección leve por SARS-CoV-2

OBJECTIVES. During acute infection by the SARS-CoV-2 virus, myocardial involvement has been demonstrated; it is unknown if cardiovascular sequelae in patients recovered from this infection and if these are associated with global morbidity and mortality. The objective of this study was to compare myo...

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Autores principales: Baltodano-Arellano, Roberto, Cupe-Chacalcaje, Kelly, Rojas, Paol, Meneses, Giovanni, Urdanivia-Ruiz, Dante, Rafael-Horna, Eliana, Falcón-Quispe, Luis, Cachicatari-Beltrán, Ángela, Hurtado-Belizario, Karla Sue América, Lévano-Pachas, Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Nacional Cardiovascular - INCOR 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506539/
https://www.ncbi.nlm.nih.gov/pubmed/37727669
http://dx.doi.org/10.47487/apcyccv.v2i4.175
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author Baltodano-Arellano, Roberto
Cupe-Chacalcaje, Kelly
Rojas, Paol
Meneses, Giovanni
Urdanivia-Ruiz, Dante
Rafael-Horna, Eliana
Falcón-Quispe, Luis
Cachicatari-Beltrán, Ángela
Hurtado-Belizario, Karla Sue América
Lévano-Pachas, Gerald
author_facet Baltodano-Arellano, Roberto
Cupe-Chacalcaje, Kelly
Rojas, Paol
Meneses, Giovanni
Urdanivia-Ruiz, Dante
Rafael-Horna, Eliana
Falcón-Quispe, Luis
Cachicatari-Beltrán, Ángela
Hurtado-Belizario, Karla Sue América
Lévano-Pachas, Gerald
author_sort Baltodano-Arellano, Roberto
collection PubMed
description OBJECTIVES. During acute infection by the SARS-CoV-2 virus, myocardial involvement has been demonstrated; it is unknown if cardiovascular sequelae in patients recovered from this infection and if these are associated with global morbidity and mortality. The objective of this study was to compare myocardial deformation in patients recovered from mild SARS-CoV-2 virus infection with healthy controls. MATERIALS AND METHODS. This was a cross-sectional observational study that included 33 subjects recovered from mild SARS-CoV-2 infection, who were diagnosed in the previous three to six months, and 31 healthy volunteers, both groups free of cardiovascular risk factors. The study of myocardial deformation was performed using echocardiography with the speckle tracking modality. Clinical and anthropometric variables were compared. RESULTS. The 2D global longitudinal strain of the left ventricle was lower in the subjects recovered from mild SARS-CoV-2 infection than the controls (-20.2% ± 2.6 v -21.6% ± 2.4; p: 0.036). Both groups presented differences in the three ventricular levels, significant at the apical level (-21.2 ± 4.0 vs -23.4% ± 4.2; p: 0.044). The effect by levels shows an inverse Takotsubo pattern. The left ventricular ejection fraction was preserved in both groups (p: 0.153). CONCLUSIONS. Left ventricular myocardial deformation is affected in subjects recovered from mild SARS-CoV-2 infection, while the ejection fraction was found in normal ranges. Our study shows a potential role of global longitudinal strain in the detection of subclinical myocardial alterations in patients who had SARS-CoV-2.
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spelling pubmed-105065392023-09-19 Análisis comparativo de la deformación miocárdica en pacientes recuperados de infección leve por SARS-CoV-2 Baltodano-Arellano, Roberto Cupe-Chacalcaje, Kelly Rojas, Paol Meneses, Giovanni Urdanivia-Ruiz, Dante Rafael-Horna, Eliana Falcón-Quispe, Luis Cachicatari-Beltrán, Ángela Hurtado-Belizario, Karla Sue América Lévano-Pachas, Gerald Arch Peru Cardiol Cir Cardiovasc Artículo Original OBJECTIVES. During acute infection by the SARS-CoV-2 virus, myocardial involvement has been demonstrated; it is unknown if cardiovascular sequelae in patients recovered from this infection and if these are associated with global morbidity and mortality. The objective of this study was to compare myocardial deformation in patients recovered from mild SARS-CoV-2 virus infection with healthy controls. MATERIALS AND METHODS. This was a cross-sectional observational study that included 33 subjects recovered from mild SARS-CoV-2 infection, who were diagnosed in the previous three to six months, and 31 healthy volunteers, both groups free of cardiovascular risk factors. The study of myocardial deformation was performed using echocardiography with the speckle tracking modality. Clinical and anthropometric variables were compared. RESULTS. The 2D global longitudinal strain of the left ventricle was lower in the subjects recovered from mild SARS-CoV-2 infection than the controls (-20.2% ± 2.6 v -21.6% ± 2.4; p: 0.036). Both groups presented differences in the three ventricular levels, significant at the apical level (-21.2 ± 4.0 vs -23.4% ± 4.2; p: 0.044). The effect by levels shows an inverse Takotsubo pattern. The left ventricular ejection fraction was preserved in both groups (p: 0.153). CONCLUSIONS. Left ventricular myocardial deformation is affected in subjects recovered from mild SARS-CoV-2 infection, while the ejection fraction was found in normal ranges. Our study shows a potential role of global longitudinal strain in the detection of subclinical myocardial alterations in patients who had SARS-CoV-2. Instituto Nacional Cardiovascular - INCOR 2021-12-31 /pmc/articles/PMC10506539/ /pubmed/37727669 http://dx.doi.org/10.47487/apcyccv.v2i4.175 Text en https://creativecommons.org/licenses/by-nc/4.0/Este es un artículo publicado en acceso abierto bajo una licencia Creative Commons
spellingShingle Artículo Original
Baltodano-Arellano, Roberto
Cupe-Chacalcaje, Kelly
Rojas, Paol
Meneses, Giovanni
Urdanivia-Ruiz, Dante
Rafael-Horna, Eliana
Falcón-Quispe, Luis
Cachicatari-Beltrán, Ángela
Hurtado-Belizario, Karla Sue América
Lévano-Pachas, Gerald
Análisis comparativo de la deformación miocárdica en pacientes recuperados de infección leve por SARS-CoV-2
title Análisis comparativo de la deformación miocárdica en pacientes recuperados de infección leve por SARS-CoV-2
title_full Análisis comparativo de la deformación miocárdica en pacientes recuperados de infección leve por SARS-CoV-2
title_fullStr Análisis comparativo de la deformación miocárdica en pacientes recuperados de infección leve por SARS-CoV-2
title_full_unstemmed Análisis comparativo de la deformación miocárdica en pacientes recuperados de infección leve por SARS-CoV-2
title_short Análisis comparativo de la deformación miocárdica en pacientes recuperados de infección leve por SARS-CoV-2
title_sort análisis comparativo de la deformación miocárdica en pacientes recuperados de infección leve por sars-cov-2
topic Artículo Original
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506539/
https://www.ncbi.nlm.nih.gov/pubmed/37727669
http://dx.doi.org/10.47487/apcyccv.v2i4.175
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