Cargando…

Integrating Network Pharmacology and Component Analysis to Study the Potential Mechanisms of Qi-Fu-Yin Decoction in Treating Alzheimer’s Disease

PURPOSE: To elucidate the potential mechanisms of QFY for the treatment of Alzheimer’s Disease (AD), and explore the effective substances of QFY. MATERIALS AND METHODS: UPLC-LTQ-Orbitrap-MS was used to identify the chemical constituents of the serum samples and the cerebrospinal fluid samples of rat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lei, Xia, Xu, Hongdan, Wang, Yan, Gao, Hainan, Zhao, Deping, Zhang, Jinfeng, Zhu, Ziyue, Zuo, Kun, Liu, Ying, Li, Xiaoliang, Zhang, Ning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506672/ https://www.ncbi.nlm.nih.gov/pubmed/37727255 http://dx.doi.org/10.2147/DDDT.S402624

Ejemplares similares

Qi Fu Yin–a Ming Dynasty Prescription for the Treatment of Dementia
por: Ong, Wei-Yi, et al.
Publicado: (2018)

Is Qi Fu Yin effective in clinical treatment of dementia?: A meta-analysis of 697 patients
por: Wang, Lei, et al.
Publicado: (2021)

Qi-fu-yin attenuated cognitive disorders in 5xFAD mice of Alzheimer's disease animal model by regulating immunity
por: Yang, Xiuzhao, et al.
Publicado: (2023)

Effects of Qi-Fu-Yin on aging of APP/PS1 transgenic mice by regulating the intestinal microbiome
por: Xiao, Qiu-yue, et al.
Publicado: (2023)

Identification of Chemical Components of Qi-Fu-Yin and Its Prototype Components and Metabolites in Rat Plasma and Cerebrospinal Fluid via UPLC-Q-TOF-MS
por: Li, Hengyu, et al.
Publicado: (2021)

Network Pharmacology Analysis and Molecular Characterization of the Herbal Medicine Formulation Qi-Fu-Yin for the Inhibition of the Neuroinflammatory Biomarker iNOS in Microglial BV-2 Cells: Implication for the Treatment of Alzheimer's Disease
por: Ngo, Fung Yin, et al.
Publicado: (2020)

Exploration of the Potential Mechanism of Qi Yin San Liang San Decoction in the Treatment of EGFRI-Related Adverse Skin Reactions Using Network Pharmacology and In Vitro Experiments
por: Wang, Yalei, et al.
Publicado: (2022)

The Effects of Yin, Yang and Qi in the Skin on Pain
por: Adams, James David
Publicado: (2016)

YiQi YangYin Decoction Attenuates Nonalcoholic Fatty Liver Disease in Type 2 Diabetes Rats
por: Li, Fengjin, et al.
Publicado: (2021)

Protective effect of Lai Fu Cheng Qi decoction on severe acute pancreatitis-induced myocardial injury in a rat model
por: LI, NAN, et al.
Publicado: (2015)

Tissue Pharmacology of Da-Cheng-Qi Decoction in Experimental Acute Pancreatitis in Rats
por: Zhao, Xianlin, et al.
Publicado: (2015)

Ameliorative effects of Xue-Fu-Zhu-Yu decoction, Tian-Ma-Gou-Teng-Yin and Wen-Dan decoction on myocardial fibrosis in a hypertensive rat mode
por: Zhang, Guohua, et al.
Publicado: (2016)

The chemical components, action mechanisms, and clinical evidences of YiQiFuMai injection in the treatment of heart failure
por: Lv, Shichao, et al.
Publicado: (2022)

Validation of the qi blood yin yang deficiency questionnaire on chronic fatigue
por: Kim, Jihye, et al.
Publicado: (2016)

Gene Expression Profiles of HIV/AIDS Patients with Qi-Yin Deficiency and Dampness-Heat Retention
por: Liu, Sa, et al.
Publicado: (2016)

Efficacy and safety of YinQiSanHuang-antiviral decoction in chronic hepatitis B: study protocol for a randomized, placebo-controlled, double-blinded trial
por: Wu, Qing-Juan, et al.
Publicado: (2020)

Decoding the Mechanism of Shen Qi Sha Bai Decoction in Treating Acute Myeloid Leukemia Based on Network Pharmacology and Molecular Docking
por: Jia, Guanfei, et al.
Publicado: (2021)

Therapeutic targets and signaling pathways of active components of QiLing decoction against castration-resistant prostate cancer based on network pharmacology
por: Cao, Hongwen, et al.
Publicado: (2022)

YinQiSanHuang Jiedu decoction for the treatment of hepatitis B-related compensated liver cirrhosis: study protocol for a multi-center randomized controlled trial
por: Wu, Qing-Juan, et al.
Publicado: (2021)

Study on the liver Drug’s dominant metabolic enzymes for six effective components of the Huang qi Liuyi decoction
por: Wang, Qun, et al.
Publicado: (2023)

Identifying roles of “Jun-Chen-Zuo-Shi” component herbs of QiShenYiQi formula in treating acute myocardial ischemia by network pharmacology
por: Wu, Leihong, et al.
Publicado: (2014)

Network pharmacology and experimental evidence reveal the protective mechanism of Yi-Qi Cong-Ming decoction on age-related hearing loss
por: Yang, Yi-Fang, et al.
Publicado: (2022)

In silico and in vivo demonstration of the regulatory mechanism of Qi-Ge decoction in treating NAFLD
por: Peng, Chong, et al.
Publicado: (2023)

A Network Pharmacology Approach to Uncover the Mechanisms of Shen-Qi-Di-Huang Decoction against Diabetic Nephropathy
por: Di, Sha, et al.
Publicado: (2018)

Network Pharmacology Strategy to Investigate the Pharmacological Mechanism of HuangQiXiXin Decoction on Cough Variant Asthma and Evidence-Based Medicine Approach Validation
por: Xia, Qingqing, et al.
Publicado: (2020)

Objectification of the Qi Blood Yin Yang Deficiency Pattern by Using a Facial Color Analysis
por: Park, Hye Bin, et al.
Publicado: (2017)

Therapeutic mechanism of Yīn-Chén-Hāo decoction in hepatic diseases
por: Li, Jian-Yuan, et al.
Publicado: (2017)

Effects of Huang Qi Decoction on Endothelial Dysfunction Induced by Homocysteine
por: Chu, Shuang, et al.
Publicado: (2016)

BuFeiXiaoJiYin ameliorates the NLRP3 inflammation response and gut microbiota in mice with lung cancer companied with Qi-yin deficiency
por: Jiang, Rui-yuan, et al.
Publicado: (2022)

Transcriptomic and network pharmacology approaches revealed possible mechanisms underlying the 5-fluorouracil (5-FU)-sensitizing effect of Xuan-Fu-Hua decoction treatment on liver cancer cells
por: Luo, Wen-Zhao, et al.
Publicado: (2022)

Network Pharmacology Approach Reveals the Potential Immune Function Activation and Tumor Cell Apoptosis Promotion of Xia Qi Decoction in Lung Cancer
por: Zhang, Song, et al.
Publicado: (2019)

Da-Cheng-Qi Decoction Combined with Conventional Treatment for Treating Postsurgical Gastrointestinal Dysfunction
por: Jin, Wei, et al.
Publicado: (2017)

Systematic Understanding of Mechanism of Yi-Qi-Huo-Xue Decoction Against Intracerebral Hemorrhagic Stroke Using a Network Pharmacology Approach
por: Li, Jian, et al.
Publicado: (2020)

Exploring the Mechanisms of Modified Bu-Shen-Yi-Qi Decoction for COPD-Related Osteoporosis Therapy via Transcriptomics and Network Pharmacology Approach
por: Zhong, Yuanyuan, et al.
Publicado: (2023)

Protocol for the evaluation and validation of Qi Blood Yin Yang deficiency pattern questionnaire: prospective observational study
por: Kim, Jihye, et al.
Publicado: (2015)

Effect of Zhen Qi Fu Zheng granules on the bone marrow depression model induced by Zidorf
por: Miao, Mingsan, et al.
Publicado: (2018)

ShenQi FuZheng injection as an adjunctive treatment to chemotherapy in breast cancer patients: a meta-analysis
por: Zhang, Hongbo, et al.
Publicado: (2019)

YiQiFuMai injection for chronic heart failure: Protocol for a systematic review and meta-analysis
por: Wang, Yuanping, et al.
Publicado: (2018)

Exploring the comorbidity mechanisms between asthma and idiopathic pulmonary fibrosis and the pharmacological mechanisms of Bu-Shen-Yi-Qi decoction therapy via network pharmacology
por: Zhong, Yuanyuan, et al.
Publicado: (2022)

Qi-Dong-Huo-Xue-Yin balances the immune microenvironment to protect against LPS induced acute lung injury
por: zhao, Tian, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_r4f27fc7orat3s2ceokjp50qeg