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Regulation of Axon Guidance by Slit2 and Netrin-1 Signaling in the Lacrimal Gland of Aqp5 Knockout Mice

PURPOSE: Dry eye disease (DED) is multifactorial and associated with nerve abnormalities. We explored an Aquaporin 5 (AQP5)-deficiency-induced JunB activation mechanism, which causes abnormal lacrimal gland (LG) nerve distribution through Slit2 upregulation and Netrin-1 repression. METHODS: Aqp5 kno...

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Detalles Bibliográficos
Autores principales:	Bai, Ying, Di, Guohu, Ge, Huanhuan, Li, Bin, Zhang, Kaier, Zhang, Di, Wang, Dianqiang, Chen, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2023
Materias:	Visual Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506685/ https://www.ncbi.nlm.nih.gov/pubmed/37707834 http://dx.doi.org/10.1167/iovs.64.12.27

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