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Logical gates in ensembles of proteinoid microspheres

Proteinoids are thermal proteins which swell into microspheres in aqueous solution. Ensembles of proteinoids produce electrical spiking activity similar to that of neurons. We introduce a novel method for implementing logical gates in the ensembles of proteinoid microspheres using chronoamperometry....

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Detalles Bibliográficos
Autores principales: Mougkogiannis, Panagiotis, Adamatzky, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506713/
https://www.ncbi.nlm.nih.gov/pubmed/37721941
http://dx.doi.org/10.1371/journal.pone.0289433
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author Mougkogiannis, Panagiotis
Adamatzky, Andrew
author_facet Mougkogiannis, Panagiotis
Adamatzky, Andrew
author_sort Mougkogiannis, Panagiotis
collection PubMed
description Proteinoids are thermal proteins which swell into microspheres in aqueous solution. Ensembles of proteinoids produce electrical spiking activity similar to that of neurons. We introduce a novel method for implementing logical gates in the ensembles of proteinoid microspheres using chronoamperometry. Chronoamperometry is a technique that involves applying a voltage pulse to proteinoid microspheres and measuring their current response. We have observed that proteinoids exhibit distinct current patterns that align with various logical outputs. We identify four types of logical gates: AND, OR, XOR, and NAND. These gates are determined by the current response of proteinoid microspheres. Additionally, we demonstrate that proteinoid microspheres have the ability to modify their current response over time, which is influenced by their previous exposure to voltage. This indicates that they possess a capacity for learning and are capable of adapting to their environment. Our research showcases the ability of proteinoid microspheres to perform logical operations and computations through their inherent electrical properties.
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spelling pubmed-105067132023-09-19 Logical gates in ensembles of proteinoid microspheres Mougkogiannis, Panagiotis Adamatzky, Andrew PLoS One Research Article Proteinoids are thermal proteins which swell into microspheres in aqueous solution. Ensembles of proteinoids produce electrical spiking activity similar to that of neurons. We introduce a novel method for implementing logical gates in the ensembles of proteinoid microspheres using chronoamperometry. Chronoamperometry is a technique that involves applying a voltage pulse to proteinoid microspheres and measuring their current response. We have observed that proteinoids exhibit distinct current patterns that align with various logical outputs. We identify four types of logical gates: AND, OR, XOR, and NAND. These gates are determined by the current response of proteinoid microspheres. Additionally, we demonstrate that proteinoid microspheres have the ability to modify their current response over time, which is influenced by their previous exposure to voltage. This indicates that they possess a capacity for learning and are capable of adapting to their environment. Our research showcases the ability of proteinoid microspheres to perform logical operations and computations through their inherent electrical properties. Public Library of Science 2023-09-18 /pmc/articles/PMC10506713/ /pubmed/37721941 http://dx.doi.org/10.1371/journal.pone.0289433 Text en © 2023 Mougkogiannis, Adamatzky https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Mougkogiannis, Panagiotis
Adamatzky, Andrew
Logical gates in ensembles of proteinoid microspheres
title Logical gates in ensembles of proteinoid microspheres
title_full Logical gates in ensembles of proteinoid microspheres
title_fullStr Logical gates in ensembles of proteinoid microspheres
title_full_unstemmed Logical gates in ensembles of proteinoid microspheres
title_short Logical gates in ensembles of proteinoid microspheres
title_sort logical gates in ensembles of proteinoid microspheres
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506713/
https://www.ncbi.nlm.nih.gov/pubmed/37721941
http://dx.doi.org/10.1371/journal.pone.0289433
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