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Pheochromocytoma: A Troublesome Tumor

This report presents the case of a 45-year-old man with a history of episodic headaches, palpitations, and sweating for the past six months. His blood pressure on admission was 170/100 mmHg. The patient was diagnosed with pheochromocytoma confirmed by elevated levels of plasma catecholamines and met...

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Detalles Bibliográficos
Autores principales: Patel, Tirath, Singleton, Leah A, Mejia, Michael, Senior, Amanda, Millis, Richard M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506759/
https://www.ncbi.nlm.nih.gov/pubmed/37727845
http://dx.doi.org/10.7759/cureus.45490
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author Patel, Tirath
Singleton, Leah A
Mejia, Michael
Senior, Amanda
Millis, Richard M
author_facet Patel, Tirath
Singleton, Leah A
Mejia, Michael
Senior, Amanda
Millis, Richard M
author_sort Patel, Tirath
collection PubMed
description This report presents the case of a 45-year-old man with a history of episodic headaches, palpitations, and sweating for the past six months. His blood pressure on admission was 170/100 mmHg. The patient was diagnosed with pheochromocytoma confirmed by elevated levels of plasma catecholamines and metanephrines. CT imaging revealed a 3 cm mass in the left adrenal gland with evidence of local invasion into the surrounding tissues. The patient underwent a laparoscopic adrenalectomy and was discharged on the third postoperative day with normal blood pressure. Histopathological examination confirmed the diagnosis of pheochromocytoma. The patient was followed for six months postoperatively with the resolution of symptoms and no evidence of tumor recurrence on imaging. Recurrence involves complex environment-gene interactions that are poorly understood. The diagnosis of pheochromocytoma could take several weeks to several years mainly because the symptoms are nonspecific and episodic. Although sudden death is rare, the debilitations associated with pheochromocytoma are often multisystemic with cardiovascular, emotional, and metabolic components. This case report highlights the importance of early diagnosis, appropriate management, and follow-up for pheochromocytoma.
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spelling pubmed-105067592023-09-19 Pheochromocytoma: A Troublesome Tumor Patel, Tirath Singleton, Leah A Mejia, Michael Senior, Amanda Millis, Richard M Cureus Family/General Practice This report presents the case of a 45-year-old man with a history of episodic headaches, palpitations, and sweating for the past six months. His blood pressure on admission was 170/100 mmHg. The patient was diagnosed with pheochromocytoma confirmed by elevated levels of plasma catecholamines and metanephrines. CT imaging revealed a 3 cm mass in the left adrenal gland with evidence of local invasion into the surrounding tissues. The patient underwent a laparoscopic adrenalectomy and was discharged on the third postoperative day with normal blood pressure. Histopathological examination confirmed the diagnosis of pheochromocytoma. The patient was followed for six months postoperatively with the resolution of symptoms and no evidence of tumor recurrence on imaging. Recurrence involves complex environment-gene interactions that are poorly understood. The diagnosis of pheochromocytoma could take several weeks to several years mainly because the symptoms are nonspecific and episodic. Although sudden death is rare, the debilitations associated with pheochromocytoma are often multisystemic with cardiovascular, emotional, and metabolic components. This case report highlights the importance of early diagnosis, appropriate management, and follow-up for pheochromocytoma. Cureus 2023-09-18 /pmc/articles/PMC10506759/ /pubmed/37727845 http://dx.doi.org/10.7759/cureus.45490 Text en Copyright © 2023, Patel et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Family/General Practice
Patel, Tirath
Singleton, Leah A
Mejia, Michael
Senior, Amanda
Millis, Richard M
Pheochromocytoma: A Troublesome Tumor
title Pheochromocytoma: A Troublesome Tumor
title_full Pheochromocytoma: A Troublesome Tumor
title_fullStr Pheochromocytoma: A Troublesome Tumor
title_full_unstemmed Pheochromocytoma: A Troublesome Tumor
title_short Pheochromocytoma: A Troublesome Tumor
title_sort pheochromocytoma: a troublesome tumor
topic Family/General Practice
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506759/
https://www.ncbi.nlm.nih.gov/pubmed/37727845
http://dx.doi.org/10.7759/cureus.45490
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