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First Pharmacokinetic Data of Tenofovir Alafenamide Fumarate and Tenofovir With Dolutegravir or Boosted Protease Inhibitors in African Children: A Substudy of the CHAPAS-4 Trial
BACKGROUND: We evaluated the pharmacokinetics of tenofovir alafenamide fumarate (TAF) and tenofovir in a subset of African children enrolled in the CHAPAS-4 trial. METHODS: Children aged 3–15 years with human immunodeficiency virus infection failing first-line antiretroviral therapy were randomized...
Autores principales: | Waalewijn, Hylke, Szubert, Alexander J, Wasmann, Roeland E, Wiesner, Lubbe, Chabala, Chishala, Bwakura-Dangarembizi, Mutsa, Makumbi, Shafic, Nangiya, Joan, Mumbiro, Vivian, Mulenga, Veronica, Musiime, Victor, Monkiewicz, Lara N, Griffiths, Anna L, Bamford, Alasdair, Doerholt, Katja, Denti, Paolo, Burger, David M, Gibb, Diana M, McIlleron, Helen M, Colbers, Angela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506774/ https://www.ncbi.nlm.nih.gov/pubmed/37315296 http://dx.doi.org/10.1093/cid/ciad267 |
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