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Epigenetic signature of human immune aging in the GESTALT study

Age-associated DNA methylation in blood cells convey information on health status. However, the mechanisms that drive these changes in circulating cells and their relationships to gene regulation are unknown. We identified age-associated DNA methylation sites in six purified blood-borne immune cell...

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Detalles Bibliográficos
Autores principales: Roy, Roshni, Kuo, Pei-Lun, Candia, Julián, Sarantopoulou, Dimitra, Ubaida-Mohien, Ceereena, Hernandez, Dena, Kaileh, Mary, Arepalli, Sampath, Singh, Amit, Bektas, Arsun, Kim, Jaekwan, Moore, Ann Z, Tanaka, Toshiko, McKelvey, Julia, Zukley, Linda, Nguyen, Cuong, Wallace, Tonya, Dunn, Christopher, Wood, William, Piao, Yulan, Coletta, Christopher, De, Supriyo, Sen, Jyoti, Weng, Nan-ping, Sen, Ranjan, Ferrucci, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506794/
https://www.ncbi.nlm.nih.gov/pubmed/37589453
http://dx.doi.org/10.7554/eLife.86136