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A distinct case of an 8-year-old female with cyclic neutropenia presenting with C. septicum abdominal sepsis and myonecrosis requiring a bowel resection and leg fasciotomy

Clostridium septicum is a very rare cause of severe spontaneous pediatric enterocolitis and is often associated with underlying malignancy or immunocompromise. Likewise, cyclic neutropenia is a rare congenital immunodeficiency that is characterized by cyclical periods of neutropenia, often with more...

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Autores principales: Anzinger, Harrison, Cadili, Lina, Li, Amanda, Barclay, Amanda, Hayashi, Allen H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506891/
https://www.ncbi.nlm.nih.gov/pubmed/37727224
http://dx.doi.org/10.1093/jscr/rjad512
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author Anzinger, Harrison
Cadili, Lina
Li, Amanda
Barclay, Amanda
Hayashi, Allen H
author_facet Anzinger, Harrison
Cadili, Lina
Li, Amanda
Barclay, Amanda
Hayashi, Allen H
author_sort Anzinger, Harrison
collection PubMed
description Clostridium septicum is a very rare cause of severe spontaneous pediatric enterocolitis and is often associated with underlying malignancy or immunocompromise. Likewise, cyclic neutropenia is a rare congenital immunodeficiency that is characterized by cyclical periods of neutropenia, often with more severe symptoms in the pediatric population. Here, we present a unique case of spontaneous C. septicum enterocolitis, sepsis, and myonecrosis in a child with undiagnosed cyclic neutropenia. Early recognition of pediatric sepsis, frequent reevaluation and identification of rapidly progressive infection, and early surgical intervention are critical for the effective management of a rare and severe infection.
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spelling pubmed-105068912023-09-19 A distinct case of an 8-year-old female with cyclic neutropenia presenting with C. septicum abdominal sepsis and myonecrosis requiring a bowel resection and leg fasciotomy Anzinger, Harrison Cadili, Lina Li, Amanda Barclay, Amanda Hayashi, Allen H J Surg Case Rep Case Report Clostridium septicum is a very rare cause of severe spontaneous pediatric enterocolitis and is often associated with underlying malignancy or immunocompromise. Likewise, cyclic neutropenia is a rare congenital immunodeficiency that is characterized by cyclical periods of neutropenia, often with more severe symptoms in the pediatric population. Here, we present a unique case of spontaneous C. septicum enterocolitis, sepsis, and myonecrosis in a child with undiagnosed cyclic neutropenia. Early recognition of pediatric sepsis, frequent reevaluation and identification of rapidly progressive infection, and early surgical intervention are critical for the effective management of a rare and severe infection. Oxford University Press 2023-09-18 /pmc/articles/PMC10506891/ /pubmed/37727224 http://dx.doi.org/10.1093/jscr/rjad512 Text en Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2023. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Anzinger, Harrison
Cadili, Lina
Li, Amanda
Barclay, Amanda
Hayashi, Allen H
A distinct case of an 8-year-old female with cyclic neutropenia presenting with C. septicum abdominal sepsis and myonecrosis requiring a bowel resection and leg fasciotomy
title A distinct case of an 8-year-old female with cyclic neutropenia presenting with C. septicum abdominal sepsis and myonecrosis requiring a bowel resection and leg fasciotomy
title_full A distinct case of an 8-year-old female with cyclic neutropenia presenting with C. septicum abdominal sepsis and myonecrosis requiring a bowel resection and leg fasciotomy
title_fullStr A distinct case of an 8-year-old female with cyclic neutropenia presenting with C. septicum abdominal sepsis and myonecrosis requiring a bowel resection and leg fasciotomy
title_full_unstemmed A distinct case of an 8-year-old female with cyclic neutropenia presenting with C. septicum abdominal sepsis and myonecrosis requiring a bowel resection and leg fasciotomy
title_short A distinct case of an 8-year-old female with cyclic neutropenia presenting with C. septicum abdominal sepsis and myonecrosis requiring a bowel resection and leg fasciotomy
title_sort distinct case of an 8-year-old female with cyclic neutropenia presenting with c. septicum abdominal sepsis and myonecrosis requiring a bowel resection and leg fasciotomy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506891/
https://www.ncbi.nlm.nih.gov/pubmed/37727224
http://dx.doi.org/10.1093/jscr/rjad512
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