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Structure of human drug transporters OATP1B1 and OATP1B3

The organic anion transporting polypeptides OATP1B1 and OATP1B3 are membrane proteins that mediate uptake of drugs into the liver for subsequent conjugation and biliary excretion, a key step in drug elimination from the human body. Polymorphic variants of these transporters can cause reduced drug cl...

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Detalles Bibliográficos
Autores principales:	Ciută, Anca-Denise, Nosol, Kamil, Kowal, Julia, Mukherjee, Somnath, Ramírez, Ana S., Stieger, Bruno, Kossiakoff, Anthony A., Locher, Kaspar P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507018/ https://www.ncbi.nlm.nih.gov/pubmed/37723174 http://dx.doi.org/10.1038/s41467-023-41552-8

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