Loss of Grin2a causes a transient delay in the electrophysiological maturation of hippocampal parvalbumin interneurons

N-methyl-D-aspartate receptors (NMDARs) are ligand-gated ionotropic glutamate receptors that mediate a calcium-permeable component to fast excitatory neurotransmission. NMDARs are heterotetrameric assemblies of two obligate GluN1 subunits (GRIN1) and two GluN2 subunits (GRIN2A-GRIN2D). Sequencing da...

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Detalles Bibliográficos
Autores principales: Camp, Chad R., Vlachos, Anna, Klöckner, Chiara, Krey, Ilona, Banke, Tue G., Shariatzadeh, Nima, Ruggiero, Sarah M., Galer, Peter, Park, Kristen L., Caccavano, Adam, Kimmel, Sarah, Yuan, Xiaoqing, Yuan, Hongjie, Helbig, Ingo, Benke, Tim A., Lemke, Johannes R., Pelkey, Kenneth A., McBain, Chris J., Traynelis, Stephen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507040/
https://www.ncbi.nlm.nih.gov/pubmed/37723282
http://dx.doi.org/10.1038/s42003-023-05298-9

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