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Epidemiological features and consequences of COVID‐19 in patients with and without gastrointestinal symptoms in southwestern Iran. A retrospective observational study

BACKGROUND AND AIMS: Some studies have shown that in addition to respiratory symptoms, gastrointestinal (GI) manifestations reported in patients with coronavirus disease 2019 (COVID‐19). The aim of this study was to compare the epidemiological features and consequences of COVID‐19 in patients with a...

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Autores principales: Azarbakhsh, Habibollah, Moftakhar, Leila, Valipour, Aliasghar, Mirahmadizadeh, Alireza, Moradi, Hekmat Allah, Piraee, Elahe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507146/
https://www.ncbi.nlm.nih.gov/pubmed/37732104
http://dx.doi.org/10.1002/hsr2.1499
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author Azarbakhsh, Habibollah
Moftakhar, Leila
Valipour, Aliasghar
Mirahmadizadeh, Alireza
Moradi, Hekmat Allah
Piraee, Elahe
author_facet Azarbakhsh, Habibollah
Moftakhar, Leila
Valipour, Aliasghar
Mirahmadizadeh, Alireza
Moradi, Hekmat Allah
Piraee, Elahe
author_sort Azarbakhsh, Habibollah
collection PubMed
description BACKGROUND AND AIMS: Some studies have shown that in addition to respiratory symptoms, gastrointestinal (GI) manifestations reported in patients with coronavirus disease 2019 (COVID‐19). The aim of this study was to compare the epidemiological features and consequences of COVID‐19 in patients with and without GI symptoms. METHODS: This retrospective observational study concluded on 15,323 COVID‐19 patients with GI symptoms and 95,724 patients without symptoms. All symptoms and comorbidities of the patients collected. To investigate the differences between qualitative variables in the two groups, χ (2) test was used. Logistic regression analysis also used to identify determinants of mortality in patients with COVID‐19. RESULTS: During the course of the study, 111,047 cases of COVID‐19 occurred. Of these, 13.8% of patients had GI symptoms, and 9.9% of deaths due to COVID‐19 occurred in these patients. The most common reported GI symptoms among COVID‐19 patients were nausea, vomiting, and diarrhea. In addition, comorbidities, such as diabetes, cardiovascular disease, and thyroid disease were significantly higher in patients with GI symptoms. The result of multiple logistic regression showed that the chance of mortality is higher in a patient with COVID‐19 who have dyspnea, fever, cough, hypertension, cardiovascular disease, diabetes, immunodeficiency, chronic kidney disease, thyroid disease, chronic pulmonary disease, and male gender. The chance of death was lower in people with GI symptoms. CONCLUSION: According to the findings of this study, nausea, vomiting, and diarrhea were the most common GI symptoms. Also, the chance of death is higher in people with co‐morbidities such as cardiovascular diseases, diabetes, and high blood pressure. Therefore, it is necessary to follow these people closely.
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spelling pubmed-105071462023-09-20 Epidemiological features and consequences of COVID‐19 in patients with and without gastrointestinal symptoms in southwestern Iran. A retrospective observational study Azarbakhsh, Habibollah Moftakhar, Leila Valipour, Aliasghar Mirahmadizadeh, Alireza Moradi, Hekmat Allah Piraee, Elahe Health Sci Rep Original Research BACKGROUND AND AIMS: Some studies have shown that in addition to respiratory symptoms, gastrointestinal (GI) manifestations reported in patients with coronavirus disease 2019 (COVID‐19). The aim of this study was to compare the epidemiological features and consequences of COVID‐19 in patients with and without GI symptoms. METHODS: This retrospective observational study concluded on 15,323 COVID‐19 patients with GI symptoms and 95,724 patients without symptoms. All symptoms and comorbidities of the patients collected. To investigate the differences between qualitative variables in the two groups, χ (2) test was used. Logistic regression analysis also used to identify determinants of mortality in patients with COVID‐19. RESULTS: During the course of the study, 111,047 cases of COVID‐19 occurred. Of these, 13.8% of patients had GI symptoms, and 9.9% of deaths due to COVID‐19 occurred in these patients. The most common reported GI symptoms among COVID‐19 patients were nausea, vomiting, and diarrhea. In addition, comorbidities, such as diabetes, cardiovascular disease, and thyroid disease were significantly higher in patients with GI symptoms. The result of multiple logistic regression showed that the chance of mortality is higher in a patient with COVID‐19 who have dyspnea, fever, cough, hypertension, cardiovascular disease, diabetes, immunodeficiency, chronic kidney disease, thyroid disease, chronic pulmonary disease, and male gender. The chance of death was lower in people with GI symptoms. CONCLUSION: According to the findings of this study, nausea, vomiting, and diarrhea were the most common GI symptoms. Also, the chance of death is higher in people with co‐morbidities such as cardiovascular diseases, diabetes, and high blood pressure. Therefore, it is necessary to follow these people closely. John Wiley and Sons Inc. 2023-09-18 /pmc/articles/PMC10507146/ /pubmed/37732104 http://dx.doi.org/10.1002/hsr2.1499 Text en © 2023 The Authors. Health Science Reports published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Research
Azarbakhsh, Habibollah
Moftakhar, Leila
Valipour, Aliasghar
Mirahmadizadeh, Alireza
Moradi, Hekmat Allah
Piraee, Elahe
Epidemiological features and consequences of COVID‐19 in patients with and without gastrointestinal symptoms in southwestern Iran. A retrospective observational study
title Epidemiological features and consequences of COVID‐19 in patients with and without gastrointestinal symptoms in southwestern Iran. A retrospective observational study
title_full Epidemiological features and consequences of COVID‐19 in patients with and without gastrointestinal symptoms in southwestern Iran. A retrospective observational study
title_fullStr Epidemiological features and consequences of COVID‐19 in patients with and without gastrointestinal symptoms in southwestern Iran. A retrospective observational study
title_full_unstemmed Epidemiological features and consequences of COVID‐19 in patients with and without gastrointestinal symptoms in southwestern Iran. A retrospective observational study
title_short Epidemiological features and consequences of COVID‐19 in patients with and without gastrointestinal symptoms in southwestern Iran. A retrospective observational study
title_sort epidemiological features and consequences of covid‐19 in patients with and without gastrointestinal symptoms in southwestern iran. a retrospective observational study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507146/
https://www.ncbi.nlm.nih.gov/pubmed/37732104
http://dx.doi.org/10.1002/hsr2.1499
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